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Re: NAC causing low blood pressure?

Posted by Questionmark on May 18, 2011, at 18:44:50

In reply to Re: NAC causing low blood pressure?, posted by SLS on April 23, 2011, at 6:17:43

i don't understand why i never feel anything from NAC, when so many other people talk of noticing effects from a dose as low as 500mg! i'm taking 3g/day, and i'm usually really sensitive to substances. (Does make me wonder if maybe i personally "need" that much more NMDA inhibition though.)

Anyway, i have never noticed any lightheadedness (or anything else), even taking 2 or sometimes 3g at once. But of course that doesn't mean it's not possible for someone to. I think keeping it at a low dose is a good idea if you want to stick with it but the side effects are too much.
If you're not sure if the NAC is causing this though, you could consider taking a hefty dose say shortly before you go to bed, to see if does indeed cause what you're feeling.


Blueberry, i notice you often like to point out the benefits of trying low doses of substances, or suggesting low doses, which is a GREAT point in many cases, and very insightful of you. This is one of the [many] great flaws in psychiatry-- the failure to recognize how less is often best.

i do question if your reason for NAC's subjective effects may not be quite right though. It *could* be a result of increased glutathione production and the effects that that has, but some or all of its noticeable effects could simply be due to its inhibition of glutamate release. And in my experience the literature seems to focus on this aspect for its role in psychiatric disorders more than the glutathione aspect. However, i could be wrong, and its benefits may solely lie in its effects on glutathione. Or maybe it's both.
I am very curious about this though.


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