Posted by Hugh on March 25, 2012, at 15:58:27
In reply to Re: Tribulus for depression ... any experiences? » Hugh, posted by Tomatheus on March 24, 2012, at 18:36:44
> So many supplements that I've tried for my depressive symptoms have stopped exerting therapeutic benefits after a day, two days, or three days that a week seems like a pretty long time to respond in comparison.
I had five or six of the best days of my life on SAMe, and then it pooped out. I had two really good weeks on NADH, and then it pooped out. I had three pretty good months on P5P, and then it pooped out. I've been doing pretty well for nearly two months now because of kefir (fermented milk). This has caused me to do a lot of reading on probiotics, and I found something that might be of interest to you, since you have schizoaffective disorder. There's a clinical trial underway using the probiotics Lactobacillus rhamnosus GG and Bifidobacterium (BB12) to treat schizophrenia. You can read about it here:
http://clinicaltrials.gov/ct2/show/NCT01242371
These two strains of probiotics are available in a product called USANA Probiotic Plus.
http://www.usana.com/webhosting/product?page=page3
BB12 lowers Interleukin-2 (IL-2) levels. The following is from http://crohns.net/Miva/education/articles/Probiotics_Research.shtml
IL-2 production from PBMC in the Bb12 group was significantly lower compared with the other groups.
The following is from http://www.cytokines-and-depression.com/chapter7.html
Interleukin-2 (IL2) and Interferon-Gamma (INFγ) INFγ and IL2 are primarily secreted by T-lymphocytes. Low doses of IL-2 produce symptoms of depression. Severe lethargy, impaired memory, slowed responses, impaired attention, anorexia, lack of interest and irritability are found with most volunteers after receiving low doses of IL2. High doses of IL2 provoke very severe symptoms of schizophrenia, including hallucinations, delusions, disorientation in time, place or person. These observations have prompted the development of a macrophage-lymphocyte model of schizophrenia.
poster:Hugh
thread:1013722
URL: http://www.dr-bob.org/babble/alter/20111229/msgs/1013954.html