Posted by alexcanada on March 14, 2013, at 1:27:28
In reply to Re: any way to calm down DA/NE? » g_g_g_unit, posted by SLS on August 2, 2012, at 12:42:58
Hi Scott. I'm glad you continue to post regularly as your posts are usually a wealth of knowledge.
Lamictal for me had very positive effect on mood and ability to feel some happiness but I felt progressively more tired and extremely cognitively dull. I felt more stupid by the day.
You mention lamictal being a glutamate suppresent. What other meds or substances are glut suppressants? Or what might give me the benefits of Lamictal but without the cognitive detriment?
Any insight at all would be greatly appreciated.
-strong melancholic depression, very poor drive, motivation, interest, cognition.
> NAC is a good guess. It was the first thing that popped into my head as I began reading your post. You might be experiencing overactive glutamate circuits secondary to NE activation. NAC dampens glutamate hyperactivity. It is certainly worth a try. NAC is a rather benign substance. I tried it, but I felt more depressed during the first week. I discontinued it at that point. Looking back on it, my worsened state could have been the natural course of my illness. I never rechallenged myself with it. NAC might be a good adjunct to Lamictal, another glutamate suppressant. A friend of mine is currently trying this combination along with low-dosage Abilify.
>
>
> - Scott
poster:alexcanada
thread:1022616
URL: http://www.dr-bob.org/babble/alter/20120530/msgs/1040292.html