Posted by ShawnThomas on January 21, 2008, at 20:21:37
In reply to Drugs that affect dopamine levels + receptors, posted by ShawnThomas on January 21, 2008, at 12:34:21
Sorry, I left some drugs out and listed the ones that I know of below. You can go to http://www.accessdata.fda.gov/scripts/cder/drugsatfda/
to find the prescribing inserts that I mention. That's a great web site that allows you to access all sorts of information about FDA approved drugs and drug approvals listed by month. Bookmark it today. Again, go to http://www.neurotransmitter.net/drug_reference.html for citations for the drugs that don't have a reference listed. I need to remember to update that page; I'll do it sometime this week.isocarboxazid (Marplan; irreversible inhibitor of monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B))
rotigotine (Neupro; agonist at D1, D2, and D3 receptors; see the prescribing label)
lisdexamfetamine (Vyvanse; prodrug of dextroamphetamine; see the prescribing label)
paliperidone (Invega; antagonist at D2L, D2S, D3, and D4 receptors; see http://pubmed.gov/7520908)
phenelzine (Nardil; irreversible inhibitor of MAO-A and MAO-B; also inhibits GABA transaminase and alanine transaminase)
selegiline, which I mentioned previously, is also an irreversible inhibitor of MAO-A and MAO-B at antidepressant doses; it may also bind to alpha-2B-adrenoceptors (see the prescribing label).
tranylcypromine (Parnate; irreversible inhibitor of MAO-A and MAO-B)
Finally, the drug amantadine may increase dopamine release and dopamine reuptake, but I need to investigate this further before making any conclusions.
Shawn
poster:ShawnThomas
thread:807927
URL: http://www.dr-bob.org/babble/neuro/20080114/msgs/808235.html