Posted by djmmm on September 14, 2003, at 7:59:02
In reply to E and Abilify, posted by Linzie on September 13, 2003, at 0:04:17
> so, granted i shouldnt do e on perscription drugs, but the past few times since ive been on abilify, esctasy does NOTHING to me, and gets all my friends fucked up.... is there some weird combo thing going on? anyone?
>
> thanks!Yeah..I would say that combining the two creates a mess of pharmacological interactions...it's best to avoid E while on any other psychoactive meds (antidepressants or otherwise)...MDMA has a variety of actions in your brian, effecting various neurotransmitters, as does Abilify...
As to why you aren't "feeling" the effects, this is partially due to Abilify competitivly blocking the specific (most likely serotonin) receptors that MDMA utilizes. SSRI users (specifically the more potent SSRIs) also experience an attenuated or completely abolished high when they take MDMA.
From personal experience, in the long run, taking E isn't worth it.
poster:djmmm
thread:259537
URL: http://www.dr-bob.org/babble/subs/20030903/msgs/259864.html