Posted by Susan J on October 1, 2003, at 14:27:41
In reply to Serious Problem: SSRI's making depression worse, posted by John1022 on October 1, 2003, at 10:58:59
Hi, I haven't used all the SSRIs you've talked about by I have experience with Paxil, which made my depression different and worse, and Wellbutrin, which made me angry/anxious for a while and now that's subsided.
>>1) Has anyone ever heard of these medications making the depression much worse, when something like Effexor has worked for me in the past?
<<Paxil made me worse, even making me want to die. I was on it for about a year. The week after I stopped taking it was the best week of my life. I felt so good and had great energy, and then I crashed into depression again.>>2) Is there a medication anyone can recommend that I try to help boost my seretonin that might not have these devasting affects as the medications I have tried?
<<SSRIs work on seratonin and Wellbutrin works or norepinephrine and dopamine. I don't know which one are best for you, but they do work differently. Wellbutrin seems to be more stimulating for me while SSRIs put me to sleep.>>7) Could the ringing in the ears and subsequent intolerance to Effexor and Amitriptlyine have anything to do with each other? (because of the fact when I take them my ears pop, jaw cracks, hearing sensitivity increases)
<<I don't know from personal experience, but my mother has had tinnitus as a side effect from certain drugs....>>8) Is this some kind of seretonin toxicity that won't allow me to take to Effexor? It almost seems like the Effexor and Amitriptyline are making the seretonin problems much worse.
<<I don't know about drug interactions, either, but have been warned not to take multiple drugs that affect seratonin because it might cause toxicity.*Also* I do know that it took a long time for me to get rid of side effects and for the drugs to kick in fully. It took about 2 months on each drug before I really started noticing a good difference, and Paxil's side effects lasted the entire time I took the drug. I don't know if you've tried all these different drugs in a 2 month period whether there's been enough time for any particular drug to kick in properly. I think everyone is different on that, and I think the way you react to drugs can change over time.
Good luck, though. I hope someone else has better answers to your questions than I do. Hang in there.
Susan
poster:Susan J
thread:264703
URL: http://www.dr-bob.org/babble/subs/20030903/msgs/264750.html