Posted by squids on January 4, 2004, at 18:55:06
In reply to Re: To Lindsay..., posted by Lindsay Rae on January 3, 2004, at 22:11:25
> > To Lindsey
> >
> Mike, you're right about Bup, but unfortunately I'm not a prime candidate. Going from H to Bup is ideal. From Methadone, you must be down to at least 30 mg to attempt the switch, and once you take the Bup, the antagonist properties clear the Methadone from the receptors causing instant withdrawal. It's a tricky drug, being a partial agonist. Pharmacists and doctors alike are baffled by this property--no other med is considered a partial agonist. I'm not looking to get off Methadone because I have extensive back problems that would leave me immobile without it. Do you know if Bup is effective for pain as well? Thanks!I'm not an expert for sure, but I do believe Bup is effective for pain too. Yeah, it's tricky with the mixed ag/antag action. I was told above 1g H/day and I couldn't take it cause it would send me into instant withdrawals. Luckily I managed to get myself down to 1g on my own before going on Bup. Below is a bit of info from some site about Bup for pain. Trade name is Temgesic.
Buprenorphine belongs to a group of medicines called opioids. Opioids mimic the effects of naturally occurring pain reducing chemicals (endorphins). They combine with the opioid receptors in the brain and block the transmission of pain signals.
This preparation is commonly used to relieve pain associated with heart attack, injury, surgery and cancer. Buprenorphine has a lower potential for producing dependence than some other opioid pain relievers and so acts as a useful alternative in opioid dependant people.
poster:squids
thread:290969
URL: http://www.dr-bob.org/babble/subs/20031208/msgs/296468.html