Posted by rod on June 10, 2005, at 4:35:04 [reposted on June 10, 2005, at 18:28:00 | original URL]
In reply to Re: I think I am going to start smoking, posted by linkadge on June 9, 2005, at 17:34:00
> Yes, drugs that generally increase acetycholine function tend to decrease noradrenic function.
>
> They call it the cholinergic-adrenergic axis. I found a good explaination on the cover of www.nootropics.com as to how oftentimes so-called "smart drugs" tend to induce depression. As well there is the term "dumb drug euphoria", whereby certain drugs like anticholinergics (cogentin etc) that produce cognative dysfunction, can actually produce a "mindless euphoria".
>
> Linkadge
>Yup, exactly.
Most "smart drugs" make me even more depressed.
Anticholinergic drugs seem to be the only ADs which work for me. And I would say the cognitive deficit caused by depression is far worse than the one induced by anticholinergics. I tried both Biperiden and Procyclidine. Procyclidine has mood elevating and stimulating properties, but Procyclidine is a bit anxiogenic on the long term, for me. And believe it or not, my cognition improves on low dose procyclidine!
And about smoking. I tried to substitute smoking with nicotine inhaler/gums/patches, but nicotine alone seems to cause more stress, causes the release of cortisol. This feeling is the exact one like when I crash on Ritalin, or after doing sports..
But smokng tobaco seems the have an anti stress efect on me. smoking a few has a similar anti stress effect like DHEA, cranial electro stimulation (which also has some anti stress/cortisol effect on higher frequencies. But I dont do that anymore because I dont want to demeylenate my nerve fibres ;) ). I guess other ingredients compensate the negative effect of nicotine induced release of cortisol... or other transmitter systems
Cigarettes really do something what nicotine alone does not do for me.
my 2 centRoland
poster:rod
thread:510720
URL: http://www.dr-bob.org/babble/subs/20050602/msgs/510739.html