Posted by Deus_Abscondis on December 18, 2006, at 21:12:38
In reply to Re: Selegiline (Eldepryl) AND Tianeptine (Stablon), posted by Declan on December 18, 2006, at 13:20:11
Thanks but what does "too dopaminergic" feel like to you?
I'll have to check dopamine (DA) binding for Tianeptine (Stablon). I thought it was quite selective, but even if DA binding is low I guess some 'serotonin neurons' meet up with dopamine ones somewhere?
After all the pharmaceutical company hype about serotonin deficiency my doctor raised his eyebrows when I told him about the putative action of tianeptine. Wouldn't a re-uptake enhancer lead to lower synaptic levels or would feedback maintain them?
I'm quite concerned about reports that SSRIs may create long lasting or permanent changes in neural function (e.g., reduction in receptors, permanent sexual side effects)
For me SSRIs (Prozac, Zoloft) feel like emotional anaesthetics - not mood lifting.
poster:Deus_Abscondis
thread:710708
URL: http://www.dr-bob.org/babble/subs/20060727/msgs/714897.html