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Re: Cannabis-Why do I respond well? » Tom Twilight

Posted by Chairman_MAO on February 21, 2007, at 12:47:27 [reposted on February 25, 2007, at 14:38:13 | original URL]

In reply to Cannabis-Why do I respond well?, posted by Tom Twilight on February 21, 2007, at 10:10:55

There are myriad mechanisms of action. Indeed, one is inhibition of CRF release (unfortunately, this comes surging back after you stop). Another is potentiation of mu-1 opioid activity (mu-2 are the ones in the brainstem that cause respiratory depression); THC is an indirect mu-opioid agonist.

Cannabis also can increase melatonin levels up to ~1000%; this is not necessarily a good thing, but it does help sleep.

I look at cannabis as nature's cold/flu tonic: kills pain, but you still can feel it enough to take care of yourself; it quells nausea, makes food taste better, eases anxiety, makes you want to drink water, etc. Of course, this is only one of probably thousands of legitimate uses of it, which is one of the primary reasons it's illegal, of course.


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