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Dr. Bob is Robert Hsiung, MD,
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Posted by JonW on August 23, 2002, at 17:56:47
In reply to Re: Moclobemide side-effects, posted by cybercafe on August 23, 2002, at 15:55:35
> >was on it for 4 weeks. It was starting to help but I stopped because I am stupid and impatient :) My hope is after 12 weeks and
>
> what dose were you taking?600mg by the end of 4 weeks.
Jon
Posted by JonW on August 23, 2002, at 18:03:19
In reply to Re: Moclobemide side-effects » JonW, posted by gypsea on August 23, 2002, at 16:12:57
> To your knowledge, can someone go directly from Nardil to Moclobemide, or would I have to take a break from Nardil?
There doesn't seem to be a definite answer to how long to wait between stopping Nardil and starting moclobemide. I asked a couple of pdocs who said to wait the 2 weeks to be safe so that is what I did. If it weren't for Geodon the depression would have hit kicked my arse.
Jon
Posted by cybercafe on August 24, 2002, at 1:22:01
In reply to Re: Moclobemide side-effects » gypsea, posted by JonW on August 23, 2002, at 18:03:19
> There doesn't seem to be a definite answer to how long to wait between stopping Nardil and starting moclobemide. I asked a couple of pdocs who said to wait the 2 weeks to be safe so that is what I did. If it weren't for Geodon the depression would have hit kicked my arse.
hmm... are you able to hold down a job while going through all of this ?
i am wondering how much to expect of myself ...
Posted by JonW on August 24, 2002, at 10:01:30
In reply to Re: Moclobemide side-effects, posted by cybercafe on August 24, 2002, at 1:22:01
> hmm... are you able to hold down a job while going through all of this ?
>
> i am wondering how much to expect of myself ...Well, I'm not able to hold down a job because of my illness so I can't really help you there. However, the depression didn't get significantly worse when I stopped -- which I attribute to Geodon, but I could be wrong. The withdrawal, for me, was pure hell and that would definitely get in the way of your job! If you do go this route you might want to try to keep working as usual, but be prepared to take some time off if you can. The withdrawal hit the hardest once I stopped completely. I did come off of Nardil relatively quickly so you may not have the problems I had if you go slow, but it is not uncommon to experience the flu-like withdrawal symptoms when stopping Nardil.
Good Luck,
Jon
Posted by cybercafe on August 24, 2002, at 21:39:26
In reply to Re: Moclobemide side-effects » cybercafe, posted by JonW on August 24, 2002, at 10:01:30
I'm hoping it's somewhat stimulating, since I tend to sleep too much as it is ....
Posted by JonW on August 24, 2002, at 22:03:20
In reply to Is moclobemide sedating or stimulating? , posted by cybercafe on August 24, 2002, at 21:39:26
> I'm hoping it's somewhat stimulating, since I tend to sleep too much as it is ....
For me it is stimulating and this would likely be the case for you as well. In clinical trials, placebo was more sedating than moclobemide.
Jon
Posted by cosis on August 25, 2002, at 15:57:01
In reply to Re: Nardil » cosis, posted by gypsea on August 23, 2002, at 14:47:45
Thanks for your information, I hope I have the same success as you do... I still havent noticed any difference but I guess a majority feel a difference in 2-4 weeks?
Yesterday I was at Old Navy and felt super anxiety, I was sweating and avoiding all eye contanct.. It was embarrassing for some reason.. I have been like this the last 2-3 years.. It is just getting worse..
When Nardil kicked in did you just feel no anxiety or self consciousness(sp) anymore? I don't understand how it can just work like that after being like this for years..
thanks
nick
Posted by gypsea on August 26, 2002, at 5:55:47
In reply to Re: Nardil, posted by cosis on August 25, 2002, at 15:57:01
> Thanks for your information, I hope I have the same success as you do... I still havent noticed any difference but I guess a majority feel a difference in 2-4 weeks?
>
> Yesterday I was at Old Navy and felt super anxiety, I was sweating and avoiding all eye contanct.. It was embarrassing for some reason.. I have been like this the last 2-3 years.. It is just getting worse..
>
> When Nardil kicked in did you just feel no anxiety or self consciousness(sp) anymore? I don't understand how it can just work like that after being like this for years..
>
> thanks
> nickNick,
It's been years, but I can relate so well to the sensation you describe having in Old Navy. Yes, that's exactly what happened once Nardil kicked in. It was incredible! All of a sudden, I had my life back! Please keep me posted as you continue with Nardil. I pray that you get the same relief! Everyone has different physiologies, so it could take a bit longer than it did for me. Also keep in mind that I take 1 mg of Klonapin as well. I've never used Nardil by itself.
All the best...
Gypsea
Posted by cosis on August 28, 2002, at 12:33:16
In reply to Nardil, posted by cosis on August 21, 2002, at 17:46:28
Hi
Just an update, my pdoc upped my dosage to 60g a day.. It's now day twelve and still not feeling any different.. My pdoc say's typically takes 2 weeks until people feel a change and sometimes up to 5 weeks, I am keeping my fingers crossed :)
Posted by gypsea on August 28, 2002, at 19:28:37
In reply to Re: Nardil, posted by cosis on August 28, 2002, at 12:33:16
> Hi
>
> Just an update, my pdoc upped my dosage to 60g a day.. It's now day twelve and still not feeling any different.. My pdoc say's typically takes 2 weeks until people feel a change and sometimes up to 5 weeks, I am keeping my fingers crossed :)Hang in there and best wishes for relief soon!
Gypsea
Posted by lawrence s. on August 29, 2002, at 1:21:10
In reply to Re: Nardil » cosis, posted by JonW on August 21, 2002, at 18:11:14
For me it seemed to take 3 to 4 months before I really knew for sure it was working on my social anxiety.
Posted by cosis on August 29, 2002, at 15:38:58
In reply to Re: Nardil, posted by lawrence s. on August 29, 2002, at 1:21:10
Why so long? I would be able to tell pretty quick...
Posted by cosis on August 30, 2002, at 18:00:30
In reply to Re: Nardil, posted by cosis on August 28, 2002, at 12:33:16
Hi,
Now on day 14 of Nardil... I haven't felt any difference in my social anxiety. I felt a bit more dizzy/sleepy/clumsy since I moved up to 60g.. I actually almost fell down the stairs today LOL.
Has anyone gone longer than 2 weeks without feeling any kind of improvement? I am hanging in there but was expecting something to happen by now :/
Posted by JonW on August 30, 2002, at 19:04:30
In reply to Re: Nardil, posted by cosis on August 30, 2002, at 18:00:30
Hi cosis,
I went 4 weeks before noticing any effect on my anxiety level. Not to discourage you, but I also went 8 weeks before stopping and things didn't get much better. Remember that 12 weeks is a full trial, and according to the anxiety disorder specialist I was working with 60mg is really the minimum dose for social phobia. Hang in there!
Jon
Posted by BK on August 30, 2002, at 22:03:24
In reply to Re: Nardil, posted by cosis on August 30, 2002, at 18:00:30
> Hi,
>
> Now on day 14 of Nardil... I haven't felt any difference in my social anxiety. I felt a bit more dizzy/sleepy/clumsy since I moved up to 60g.. I actually almost fell down the stairs today LOL.
>
> Has anyone gone longer than 2 weeks without feeling any kind of improvement? I am hanging in there but was expecting something to happen by now :/
Hi Cosis,I tried Nardil some fifteen years ago. As I recall, it was a good three weeks before i felt the results and I literally went from feeling nothing to feeling incredible. Unfortunately, it pooped-out after about three months. However, when it was working it was absolute magic! That three month period still is the happiest time of my life. So, hang in there, be patient and think positively!
Posted by cosis on August 30, 2002, at 22:56:35
In reply to Re: Nardil, posted by BK on August 30, 2002, at 22:03:24
Thanks for your comments, did you find out why it stopped working?
Posted by gypsea on August 31, 2002, at 11:32:32
In reply to Re: Nardil, posted by cosis on August 30, 2002, at 22:56:35
cosis,
I just want to remind you that for over 11 years Nardil has been responsible for completely relieving my social phobia/anxiety. Think positively and HANG IN THERE! Obviously we all respond to medications differently, but I hope Nardil begins working wonders for you real soon! (Also keep in mind that I've been using it in conjunction with a benzodiazapine.)
Gypsea
Posted by cosis on September 2, 2002, at 23:56:59
In reply to Nardil, posted by cosis on August 21, 2002, at 17:46:28
Hey just a quick update on Nardil, I am starting to notice my mood changing for the better. I use to feel real suffocated when my sister (who lives with me) would always be around. I would become short with her and moody. The last few day's though I haven't felt this way at all.. it is strange not feeling it after it being a habit.
As for the social anxiety it I still haven't noticed any difference...
Side effects are minimal for me at 60g. Sometimes I can't stop myself from talking even if it's to myself.. I still get dizzy sometimes and feel a little like my head is in the clouds.. These do not both me much though..
Thanks for your input from the people who reply.
Nick
Posted by action_jackson on September 3, 2002, at 15:03:22
In reply to Re: Nardil, posted by cosis on September 2, 2002, at 23:56:59
Nick -
Awesome!
A few years back - someone told me "Just pretend that Nardil was a NEW drug".
Chad
http://www.socialfear.com/> Hey just a quick update on Nardil, I am starting to notice my mood changing for the better. I use to feel real suffocated when my sister (who lives with me) would always be around. I would become short with her and moody. The last few day's though I haven't felt this way at all.. it is strange not feeling it after it being a habit.
>
> As for the social anxiety it I still haven't noticed any difference...
>
> Side effects are minimal for me at 60g. Sometimes I can't stop myself from talking even if it's to myself.. I still get dizzy sometimes and feel a little like my head is in the clouds.. These do not both me much though..
>
> Thanks for your input from the people who reply.
>
> Nick
Posted by Blah on October 6, 2002, at 20:36:07
In reply to Nardil, posted by cosis on August 21, 2002, at 17:46:28
I've suffered from Depression and Anxiety my entire life. My Parents were very emotionaly abusive in inconsistent ways, and I had no friends at all in school, in fact I was tortured on a daily basis. I started deep analasis 3 times a week at 5 years old. It helped some, but I have been in some form of treatment ever since. I am now 28. I have tryed over 10 antidepressants including one triciclicate, prozac, zoloft, paxil, serzone, effexor, welbutrin, trazidone, rameron, and some more I can't remember. These antidepressants not only didn't work, but each actually hurt with cripling side effects. I have also tryed 2 stimulants.
I have always had terrible problems with depression, anxiety, concentration, negative thoughts, social skills, insomnia, motivation, and other problems my whole life, and have been fighting them my whole life, but its just gotten worse and worse over the years. I now live on SSI, I haven't had a romantic relationship in over a decade, and I have no energy or concentration to do any of the things I want to do. For a year or so now being around people has been the only thing that made me feel better, but now even that feels empty or hopeless most of the time.
I'm on .5 of Klonopin twice a day, and I started Nardil a little less than 3 weeks ago. I'm at 45mg now, but will probably go up to 60 tomarrow. When I can get up a good mood the Klonopin helps a bit but not much. The Nardil has done nothing so far (no side effects either though, which is good considering my past history). Within the last few weeks I've lost what little hope I had left, because of events in my life. I feel no woman can ever want me, that no one could ever care about the things i've always wanted to do, that I am too far behind in life, a total loss of energy (not that I had much to begin with), fantasising just fills me with feelings of guilt or pointlessness, and just total hopelessness. But in the end these are only the enevetable result of my lifelong mental illness. I know I have another 2-6 weeks before I may show results and I will hold out, but everyday is just something to be struggled through as I wait for this "miraculous change" that is supposed to occur. Also, when talking bout antidepressants people keep saying things like: "I have my life back," "I'm me again," "I feel Normal again." I've never had my life or happieness or funtionality, EVER. It's always been nothing but lonelyness and pain, it's just gotten worse over time. Can this or any drug really help me achive the confidecnce, possibilities for joy, and social conection that I've never really known. I've always had both hypervidulance and mood sencetivity as long as I can remember. I'm not sure what I'm asking, really I just need something to keep me going while I wait for Nardil to work. The MAOIs are really my last hope. I don't know how much longer I can go on. I have a therapist I like, but after my history she can only do so much. I'm checking out a day program at a hospital, but I've had so much therapy already, and the idea of entering such a comprehencive program seems like more time spent after bad.
PS
If you reply: Please no talk of CBT or DBT I tryed it and found it counter productive.I am not willing to have ECT which I belive to cause brain damage, and which is temporary anyway.
Please no self rightious talk of self-esteem or loving myself. This only fills me with more shame, and really doesn't say anything since no one has perfect self-esteem.
Sorry bout my bad spelling I didn't spell check.
-Thanks
Posted by cosis on October 6, 2002, at 21:08:22
In reply to Nardil and the end of a long road., posted by Blah on October 6, 2002, at 20:36:07
Hi There,
My Nardil experience didn't kick in until just past the 4th week at 75mg, I am at 90mg right now.. but I didn't get any side effects until about the 5-6 week which the worst being anorgasmia which I am crossing my fingers will go away like it does for most.. Just hang in there
Posted by Blah on October 7, 2002, at 1:26:35
In reply to Re: Nardil and the end of a long road., posted by cosis on October 6, 2002, at 21:08:22
> Hi There,
>
> My Nardil experience didn't kick in until just past the 4th week at 75mg, I am at 90mg right now.. but I didn't get any side effects until about the 5-6 week which the worst being anorgasmia which I am crossing my fingers will go away like it does for most.. Just hang in thereBut have the possitive effects gotten better? Do you have anymore confidence either with people or doing things alone. Does it stop you from thinking too much. For instance I never learned to ride a bike, and it is very hard for me cause it is something you have to not think about too much, but I think of everything I am doing I can't stop, and I'm having other counter productive thoughts too. Are symtems like these going away. Do you feel more energized, can you concentrate more, do you feel less worthless or inadiquate. Can you do more in a day than you could before. And how dramatic is the difference. How capable are you at escaping yourself? I have not had any side effects yet. It is the possitive effects I care about. I will deal with side effects as they come, but if the drug doesn't work on my cripling symtoms, or doesn't do much for them, then the side effects are irrelivant cause I will dump the drug. Has the drug helped you enough to make it worth it, please be descriptive on how it has helped and how it hasn't.
-Thanks
Posted by cosis on October 7, 2002, at 8:50:32
In reply to Re: Nardil and the end of a long road., posted by Blah on October 7, 2002, at 1:26:35
Hi,
Yes they got better, My problem was pretty moderate social anxiety disorder w/ a little bit of depresseion. I do have more confidence now than before. I think it also helped my from overanalizing things. I also feel more energized, especially in the morning. I wake up now at 6am-7am when I use to have to set my alarm at 9am to wake up. And when I did wake up I was still out of it. Now I wake up with energy and a clear head. I am able to do more since I wake up 2-3 hours earlier now and also am not as afraid of social activities as I was.
The drug has helped me not feel nearly as much anxiety as I was when around people, I can go to the mall or store now without being so self-conscious or sweating. I am even thinking of going back to college now in the srping. The first thing I noticed was a mood improvement. I use to get moody and when I got moody I was depressed some nights which doesn't happened anymore. I am more talkative also, but still somewhat shy. I hope to get over this though with exposure. Overall I am happy with the drug. The positive effects outway the side effects.
The only side effect to bother me was anorgasmia which occurred about the 5 week, then totally shut off by the 6-7 week. I have not had a orgasm in about 2 weeks now. This is the only side effect I really do not like. I hope though it diminishes over the next 1-3 months.....
-Nick
Posted by Blah on October 8, 2002, at 23:12:49
In reply to Nardil and the end of a long road., posted by Blah on October 6, 2002, at 20:36:07
> I've suffered from Depression and Anxiety my entire life. My Parents were very emotionaly abusive in inconsistent ways, and I had no friends at all in school, in fact I was tortured on a daily basis. I started deep analasis 3 times a week at 5 years old. It helped some, but I have been in some form of treatment ever since. I am now 28. I have tryed over 10 antidepressants including one triciclicate, prozac, zoloft, paxil, serzone, effexor, welbutrin, trazidone, rameron, and some more I can't remember. These antidepressants not only didn't work, but each actually hurt with cripling side effects. I have also tryed 2 stimulants.
>
> I have always had terrible problems with depression, anxiety, concentration, negative thoughts, social skills, insomnia, motivation, and other problems my whole life, and have been fighting them my whole life, but its just gotten worse and worse over the years. I now live on SSI, I haven't had a romantic relationship in over a decade, and I have no energy or concentration to do any of the things I want to do. For a year or so now being around people has been the only thing that made me feel better, but now even that feels empty or hopeless most of the time.
>
> I'm on .5 of Klonopin twice a day, and I started Nardil a little less than 3 weeks ago. I'm at 45mg now, but will probably go up to 60 tomarrow. When I can get up a good mood the Klonopin helps a bit but not much. The Nardil has done nothing so far (no side effects either though, which is good considering my past history). Within the last few weeks I've lost what little hope I had left, because of events in my life. I feel no woman can ever want me, that no one could ever care about the things i've always wanted to do, that I am too far behind in life, a total loss of energy (not that I had much to begin with), fantasising just fills me with feelings of guilt or pointlessness, and just total hopelessness. But in the end these are only the enevetable result of my lifelong mental illness. I know I have another 2-6 weeks before I may show results and I will hold out, but everyday is just something to be struggled through as I wait for this "miraculous change" that is supposed to occur. Also, when talking bout antidepressants people keep saying things like: "I have my life back," "I'm me again," "I feel Normal again." I've never had my life or happieness or funtionality, EVER. It's always been nothing but lonelyness and pain, it's just gotten worse over time. Can this or any drug really help me achive the confidecnce, possibilities for joy, and social conection that I've never really known. I've always had both hypervidulance and mood sencetivity as long as I can remember. I'm not sure what I'm asking, really I just need something to keep me going while I wait for Nardil to work. The MAOIs are really my last hope. I don't know how much longer I can go on. I have a therapist I like, but after my history she can only do so much. I'm checking out a day program at a hospital, but I've had so much therapy already, and the idea of entering such a comprehencive program seems like more time spent after bad.
>
> PS
> If you reply: Please no talk of CBT or DBT I tryed it and found it counter productive.
>
> I am not willing to have ECT which I belive to cause brain damage, and which is temporary anyway.
>
> Please no self rightious talk of self-esteem or loving myself. This only fills me with more shame, and really doesn't say anything since no one has perfect self-esteem.
>
> Sorry bout my bad spelling I didn't spell check.
>
> -ThanksUpdate, they didn't up my dose yet. The day program was a joke and I'm not going to do it. I want to sleep all the time, I don't know if its the Nardil or just the depression. I feel like I really have lost all hope, on many levels. The hopelessness and emptyness seem to overpower all of my funtioning from socializing, to housework, to doing projects I want to work on. Existence seems pointless and painful, but its hard to see how this drug will really change that. It just better work soon if it does.
Posted by Denise528 on October 10, 2002, at 13:10:33
In reply to Re: Nardil and the end of a long road., posted by Blah on October 8, 2002, at 23:12:49
Hi,
Have you tried Zyprexa? Is the Nardil not helping you at all?
Don't give up hope, there are plenty of new drugs coming on the scene, if not now, in a few years time.
Denise
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