![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 609 to 633 of 948. Go back in thread:
Posted by Dr. Bob on September 13, 2003, at 15:59:56
In reply to Re: Lithium Orotate, posted by BarbaraCat on September 13, 2003, at 14:46:24
> But anyway, on to the Lithium Orotate question...
I'd like to redirect that aspect of this thread to the new Psycho-Babble Alternative board. Here's a link:
http://www.dr-bob.org/babble/alter/20030903/msgs/259704.html
Bob
Posted by BarbaraCat on September 13, 2003, at 16:25:12
In reply to Let me run this question by you, Barb-cat, posted by fluffy on September 13, 2003, at 15:05:33
Lithium has a weak serotonergic affect, but I don't know the details. Hypomania can be an early side effect which quickly calms down. I don't remember if I got hypomania or not when I first started. As far as the bruxism, I had it really badly when I was on SSRI's. The higher dose I took, the worse it got. I was also twitchy, like a neuron would fire and a muscle would jerk. I've heard that higher doses of serotonin can cause this, but why that would be with Lithium, if it is the Li, is puzzling.
My gut feeling on this is that it's the Lamictal and not Lithium that's causing bruxism. Don't forget that Lithium is going to potentiate the effects of Lam and bruxism and other akathasia type symptoms are pretty typical when ramping up with Lam. How much are you taking of each? Have you noticed any other side effects like tremors, diarrea, nausea, blurred vision? These are the sx you'd expect with Li, but not the tension or grinding. - BCat
> Hi Barbara--
>
> You seem better today. I was worried about you. I have been, well, kinda all over the place. I had a very wierd first two weeks on Li. It did NOT have the calming effect I was expecting. In fact, I became very hypomanic and mentally confused. It seems to have calmed down. The past couple of days, I've felt I have the personality of a rock. Today is better. But what the hell??!! The most troublesome side effect I'm having that seems to be lasting is bruxism (or teeth clenching). It happens almost all day, every day--my jaw hurts really bad! Supposedly, this is related to seratonin blockage? Or something seratonin related. Does Li have much to do with Seratonin? Do you know anything about this? My doc did NOT seem pleased by the Li results!! And I can't say for certain I'm pleased yet either. My memory is better, though. My sleep has not improved yet.
>
> If you or anyone else knows about the bruxism part, i'd like to know.
>
> Thanks,
> Katy
Posted by fluffy on September 13, 2003, at 18:12:01
In reply to Re: Let me run this question by you, Barb-cat » fluffy, posted by BarbaraCat on September 13, 2003, at 16:25:12
Hey Barb-cat--
Thanks so much for fielding my question! I'm on 200mg of Lamictal, and it has always been a good dose for me. I never had ANY of the clenched teeth stuff with Lamictal alone (or even when my dose was a bit too high @250mg). The only drugs that ever gave me this problem were Zoloft and Lexapro. Maybe it's possible that I'm ultra sensitive to Lithium? I'm only on 600mg of Li. The severe side effects I had last week were ones similar to toxicity. So who knows? My doc doesn't seem to think that this reaction is from Lithium potentiating Lamictal. And I'm pretty sure he knows his stuff. (he has the pedigree, anyway) But I think he's puzzled, too.
I may give something else a try if this keeps up. Otherwise, I think I will have to refuse to titrate up on the Li. I can't stand another 2-3 weeks of alzheimer's-like confusion!
Thanks again for your thoughts.
Take care Miss Barb-cat!Katy
> Lithium has a weak serotonergic affect, but I don't know the details. Hypomania can be an early side effect which quickly calms down. I don't remember if I got hypomania or not when I first started. As far as the bruxism, I had it really badly when I was on SSRI's. The higher dose I took, the worse it got. I was also twitchy, like a neuron would fire and a muscle would jerk. I've heard that higher doses of serotonin can cause this, but why that would be with Lithium, if it is the Li, is puzzling.
>
> My gut feeling on this is that it's the Lamictal and not Lithium that's causing bruxism. Don't forget that Lithium is going to potentiate the effects of Lam and bruxism and other akathasia type symptoms are pretty typical when ramping up with Lam. How much are you taking of each? Have you noticed any other side effects like tremors, diarrea, nausea, blurred vision? These are the sx you'd expect with Li, but not the tension or grinding. - BCat
>
> > Hi Barbara--
> >
> > You seem better today. I was worried about you. I have been, well, kinda all over the place. I had a very wierd first two weeks on Li. It did NOT have the calming effect I was expecting. In fact, I became very hypomanic and mentally confused. It seems to have calmed down. The past couple of days, I've felt I have the personality of a rock. Today is better. But what the hell??!! The most troublesome side effect I'm having that seems to be lasting is bruxism (or teeth clenching). It happens almost all day, every day--my jaw hurts really bad! Supposedly, this is related to seratonin blockage? Or something seratonin related. Does Li have much to do with Seratonin? Do you know anything about this? My doc did NOT seem pleased by the Li results!! And I can't say for certain I'm pleased yet either. My memory is better, though. My sleep has not improved yet.
> >
> > If you or anyone else knows about the bruxism part, i'd like to know.
> >
> > Thanks,
> > Katy
>
>
Posted by fluffy on September 13, 2003, at 18:24:17
In reply to Re: Let me run this question by you, Barb-cat » fluffy, posted by BarbaraCat on September 13, 2003, at 16:25:12
Hi again Barb-cat--
I was just wondering...What exactly does serotonergic mean? I know it has something to do with seratonin. Does it mean that it INCREASES seratonin or DECREASES seratonin. Or--does it inhibit like an SSRI? I have no clue.
And to answer your other question--I had mostly confusion and stupor as a side effect on Lithium in the first 2 weeks. It's not so bad now. But the bruxism has been constant since the first week.
Maybe it is the Lamictal? I really don't know. I'll let you know any updates in this when I talk to my doc on tuesday.
warm wishes,
Katy
Posted by katia on September 13, 2003, at 19:48:01
In reply to Re: Let me run this question by you, Barb-cat » fluffy, posted by BarbaraCat on September 13, 2003, at 16:25:12
Hiya,
I feel like I'm being ignored, am I?I was reading your Monkey's posting Barb (btw, did you make that up?) I didn't really read the whole thing - maybe my ADD mind!? I've been thinking about that I might have ADD rather or also. And/or BPD as you said. So you tried Ritalin? No good? At least you found out.
If you did make it up - WOW! what an imagination you have there. And how wonderfully you are able to get that across in such a creative articulate way!
I started my Lamictal 5g today. You know I had two good days and then crashed again last night. It was circumstantial. But the circumstance didn't warrant me tearing out in the middle of a ceremony in tears in a HUGE crowdful of people b/c I was hurt by a friend(s). I cried the night and the morning away. And thought, "hey, I may be caught again in my mood swing. Would ANYONE have reacted like that?"
Just to let you know, I self-medicated! That'll be the code word from now on. I went straight for the beach, got another friend and bottle of dopamine and watched the sunset. Ahhhh. much better.Want to hear the most transporting music ever ever???? (ok ok alternatives board for music therapy). Arvo Part "Alina". Lovely jubley. Simple, yet conveys the deep mystical lovely beauty of life.
It helped me get thru' the night and the morning, I tell ya what!
I highly recommend it!let me know how you are. I'm a sensitive type! I think you may be upset with me.
Katia
Posted by BarbaraCat on September 13, 2003, at 20:01:39
In reply to serotonergic?, posted by fluffy on September 13, 2003, at 18:24:17
I'm not sure of the exact details (who is?), but lithium is suspected (no one knows for sure on any of this stuff) of having a weak affinity for serotonin, which means that it may have properties whereby it looks like serotonin to the serontonin receptors, but it's probably more due to the fact that Lithium works on inhibitory neurons, and the serotonin system is inhibitory.
Our Lam/Li is something we both share, so let me see if I can remember my neurophysiology and we'll try to sleuth this thing out. Lithium acts differently than the SSRI's, TCA's or any of the other meds we associate with neurotransmitter activity. The way neurons communicate is both chemically and electrically. SSRI's, TCA's, MAOI's affect amines, or the classic neurotransmitters we hear about, i.e., serotonin, norepinephrine, dopamine. These chemically stimulate receptors on the dendrites, or receiving ends of another neuron. When the receptors are stimulated, they literally wiggle and send an impulse to the neuron's cell nucleus which, once it decides what to do with this info, sends an electrical signal down to the end, or terminus of the axon, the long arm of the neuron. The information in this electrical transmission has that synaptic gap to cross and the only way to do this is by releasing chemicals (neurotransmitters) that ferry the appropriate neurotransmitter across to the next neuron's receptors and on and on.
Lithium works on the electrical system rather than the chemical, as far as anyone can tell, so it can't be described in the same terms as how the amines work at the synaptic cleft. Lithium is a metallic element and regulates the positive/negative charged ion gates on the surface of the axon. It's not too particular which neuron it acts on, so it can affect the electrical potentials of the serotonin system, and don't quote me on this but I believe also norepinephrine, dopamine, gaba, acetylcholine, and many more groups of neuro chemicals. That's why it's given as an augmentor to turn up the volume on many meds, not just for BP, but mainly SSRI's are the ones that lithium is usually prescribed for as an augmentor when they start to poop. That serotonin affinity again.
Because it acts on inhibitory neurons, you're going to get some lethargy and dullness which is a good thing if you're manic, but not good if you're feeling dopey. That's where Lamictal comes in. Why and how I do not know, but for whatever reason, it seems to balance Li's dopey effects. Like the majority of the 'mood stabilizers' Lam acts on the electrical system, but differently than Li, probably on the excitatory neurons (because it really is stimulating, I don't care what the drug pamphlets say), and both together appear to be greater than the sum. Lam probably also has chemical properties as well, but who knows, it's all so iffy.
So, the reasoning is that when you're taking Lam and Li together, you don't need as much as if you're taking them separately. I've read this in many resources and it's true for me. I'm taking 600mg of Li and that is quite adequate. My pdoc keeps wanting me to bump it up because my blood levels are therapeutically low, but if I go higher I feel horrible, get tremors, nausea, and feel blunted emotionally. Perhaps you can disuade your doc from increasing your Li levels until things sort out, and because you may not need more.
I've been doing some more research and bruxism is definitely a sx with Lam, so it could be that the lithium is making Lam behave as if it's much stronger and you're getting a fairly typical reaction of agitation from too high a dose of Lam. I've tried to increase Lam from my 125mg, especially when I was having a real hard time. I can't do it and get uncomfortable very quickly. Luckly, Lam is a fast acting drug as far as sx's go and any discomfort subsided after a few days.
Before throwing out the Lithium baby with the bathwater, when you see your pdoc you might want to discuss lowering the Lam a little and not increasing the Li for a while. You really don't need to be in that therapeutic window unless you're primarily manic and really need to come down. You're not going to lose any therapeutic ground if you go slow and you can always go back up again. With my recent downward skids, I'm probably not the Li/Lam poster child, but my setbacks are short lived and for the most part, I'm happy with my puny dosages. Plus, I'll take the occasional subtherapeutic risks of lower Li to maintain more emotional spark.
One more question. What other meds are you taking? Guess that should have been the first question before going into Neurophysiology 101. - Barbara
> I was just wondering...What exactly does serotonergic mean? I know it has something to do with seratonin. Does it mean that it INCREASES seratonin or DECREASES seratonin. Or--does it inhibit like an SSRI? I have no clue.
>
> And to answer your other question--I had mostly confusion and stupor as a side effect on Lithium in the first 2 weeks. It's not so bad now. But the bruxism has been constant since the first week.
>
> Maybe it is the Lamictal? I really don't know. I'll let you know any updates in this when I talk to my doc on tuesday.
>
> warm wishes,
> Katy
Posted by BarbaraCat on September 14, 2003, at 3:35:11
In reply to Transporting Arvo Part » BarbaraCat, posted by katia on September 13, 2003, at 19:48:01
Katia, Katia,
Ignoring you? Upset with you? Silly wench! Of course not - you is my Sis, my ally and who else would know what the heck a glass of D is? I came to the conclusion that I'm not going to be a succesful abstainer and so have made a compromise. I will allow myself to enjoy, enjoy being the operative word and not glut myself on, a nice drink or two on the weekend. Not wine, unless I'm with other people sitting around a dinner table where I'm in the public eye so I can only have a glass or two and not the whole bottle. There's something about wine that is very dangerous for me. The other stuff I can take or leave, but it makes social occasions definitely more festive and relaxed. So there I am with that one and it feels fine.Glad you had a therapeutic beach adventure with the help of the D-ster. I will definitely check out Arvo Part. I've made a note to myself. What kind of music is it?
Hope you're feeling on more stable ground. It's so hard to know what's real when the chemistry is so sensitive. When I'm feeling bad I just KNOW that no one really likes me, that I have no true friends, my family connections are gone, I'm married to a dolt, I'll end up a sick failure out on the streets covered with pustules, I'm ugly and sloppy and no matter how often I bathe I still stink and am humiliated that other people are surely thinking 'ick, she stinks'. All this becomes very real and tormenting. I see the evidence everywhere. I walk into rooms and just KNOW that they've been talking and laughing about me because I FEEL it so strongly. It hurts terribly how mean and petty and uncaring everyone is just when I really need some TLC, but I can't blame them because they're right, I really am a substandard sneaky little failure.
But that's just my sickness talking. When I've come down or up to a normal place, my thoughts clear and I'm aware of the many resources I really do have. Things are no longer so fragmented and I can pull together the pieces and see the whole picture better. I can even see the higher picture and how it might all fit into the whole. I also have better energy when I'm not sick so figuring these things out isn't so exhausting and things seems so much easier to deal with.
Of course, I'd prefer if people thought well of me, but most of the time I don't let their opinions affect me at all (except maybe for the smelly part. I'm pretty compulsive about showering). I figure that if they don't like or approve of me, well, there are a few billion other folks they can hang out with instead. When I'm feeling bad, it's hard to be in my own skin, but when I'm feeling OK, I rather like my own company quite alot. If I start ruminating about the sick old bag lady stuff which EVERYONE seems to run, then I figure that I'm resourceful enough to prevent it or see my way out of it. I take care to spend time with people I really like and since it's no longer of interest to me to win popularity contests, I'm satisfied with the quality and not quantity of my friends. My family can be weird, but so is everybody's. My husband is my best buddy even though he can be a world class ass. In short, the same situations look soooo different depending on where I'm at in my mental health. What's becoming clear is that everyone is preoccupied with their own stuff and has too little time energy or interest to spend it on putting me down or taking care of me for very long. There were so many years of hell, but I have to admit that there are more good times now than bad and I'm beginning to trust in them more and believe that it's my time finally to come to peace with my self and my life. The skids are less frequent and less intense and I'm over them more quickly. Trust is a big issue with me and probably with most of us. That's why we're depressed. We don't trust we'll ever be better and that's scary.
You're on a rollercoaster right now with all the adjustments your body and brain are going through. These meds are powerful. It's very frustrating and frightening not to know if you're on the right track with them and if you can really trust anyone to know what you need. It may take longer than you'd like, maybe not, but eventually you'll settle in with a good fit. I know you won't give up until you do.
I think that most of the anguish we put ourselves through is about worrying about what might happen, fantasizing the worst and not even noticing that the present moment is usually OK, even though it might feel rocky and uncomfortable. But the discomfort is usually caused by worry about the what ifs. Have you read "The Power of Now" by Eckhard Tolle? It's probably been the most helpful and powerful book/philosophy for me throughout this whole thing. It's alerted me to my morbid worry obsession which has completely kept me from living and enjoying my life as it is right now, no matter what.
For me, it's the fear that the discomfort will always be there, that it will get better for a while then I'll be back in the pits again and I won't be able to stand it. I project terrible circumstances where I just give up because it's too much and life becomes a living hell. That's just the illness talking, saying that I won't be able to take the pain and craziness, I'll shatter and I'll be abandoned. But it's not real and it becomes easier to recognize that scared voice that's become a habit. That's easy to say from the vantage point of feeling better, but even in the worst of times I've always been able to handle it or found some help. My survival instinct is intact enough to know that I can trust myself to help myself or get help. Sometimes life is hell and other times it's an adventure where I feel like, shoot, I'm up for the ride - bring it on! Most of the times it's just usual stuff, sometimes a little boring even, but not always the pain and suffering like it appears when I'm sick. One thing that "The Power of Now" changed for me is that I now truly know that whatever arises in the future, I'll deal with it, so not to waste time worrying about it and miss out on the here and now.
Your cycles will even out. It may feel terrible at times and you wonder if you can stand it another minute. But you always do, as evidenced by the fact that here you are, bruises and all. Remember your Witness at times like that. Maybe you're not on the right meds, but you'll perservere until you are because you're dedicated to this search with everything you've got. nYou sure helped me get in touch with some old deep issues that I wasn't aware of, so your pain isn't there only to senselessly torment you. It's also serving the greater good and you just have to trust the process. If we all just trusted the process and our own inner wisdom things would go much more smoothly on this long strange trip we're on - but then we wouldn't be mood disordered, we'd be great sages who have reached inner serenity.
And yes, I made up the Typing Monkey thing. There was a pile of washed clothes to be folded and put away, but telling the tale of how monkeys came to type seemed so much more important than mundane laundry. Love ya, Barbara
Posted by katia on September 14, 2003, at 4:31:41
In reply to Re: Transporting Arvo Part » katia, posted by BarbaraCat on September 14, 2003, at 3:35:11
Barb,
I just have to exhale because you responded to me. I'll read your post tomorrow in more detail. What I can respond to right now...>What kind of music is it?
The best you can imagine. B/c when you imagine the thoughts coming to you -- they are simply within a backdrop of this beautiful man's music. *tear drop*.Tolles's stuff. Amazingly enough, when I was in a suicidal depression last year, unable to sleep, sitting up in bed holding my head, crawling sobbing and drooling on the floor to the bathroom to stare at me in the mirror, bags and wrinkles and I'M SO SAD!!!; I'd put his tape on. At 4 am I'd listen to him and again at 8 before I walked and walked for miles in the forest. breathing and trying to "be here now". It did help. really. There's just such a story behind that w/ me. and I partook in too many glasses of d. I feel sick!
thanks for responding Barb. I needed that.
I'll respond tomorrow. and there's nothing you should be doing with your energy BUT JUST writing.
I might just cut you off and force you to channel your writing energies into something else. Not that I don't love to hear from you!!!!
Love,
KAtia
Posted by Dr. Bob on September 14, 2003, at 8:45:59
In reply to Re: please be civil » Dr. Bob, posted by BarbaraCat on September 11, 2003, at 21:52:39
Posted by fluffy on September 14, 2003, at 12:39:02
In reply to Re: serotonergic? » fluffy, posted by BarbaraCat on September 13, 2003, at 20:01:39
Wow Barb-cat!
You've done your homework! I knew I could count on you to know some of this stuff. The only other med I'm taking right now besides Li 600mg and Lam200mg is 15mg of Temazepam at night to sleep. It helps with the bruxism and my terrible sleep. I want to NOT be taking anything for sleep right now, but it is still sketchy. I don't want to raise my Li dose right now b/c I'm fearful of the stupor I experienced. I also felt a bit blunted emotionally after a couple of weeks. I don't want to have the personality of a rock. I'm feeling functional but dysphoric at this point. I still need sleep. I wonder if a pinch of zyprexa or seroquel would help my sleep and mood stability? Lots of questions for the doc!!
All in all, I feel loads better than I did a year ago. I read my diary from then to check if I had teeth clenching...OH MY GOD!! I was such a wreck!! Pages and pages of how I was really normal and just having problems with my past. It never occurred to me that I had a chemical imbalance. I remember crying and crying and feeling suicidal then. Worlds away from where i am now. I have the LUXURY of complaining about side effects!
I'm feeling close to normal today, and I just hope that I can get a normal night's sleep w/o the benzo.
Thanks so much for the info Barb-cat. I need to bookmark that post!
I hope you (and all) are well,
Katy
Posted by BarbaraCat on September 14, 2003, at 13:19:24
In reply to Re: Transporting Arvo Part » BarbaraCat, posted by katia on September 14, 2003, at 4:31:41
Thanks for the support on the writing, Katia. I needed that. I've been pecking around on a couple books that are practically writing themselves and still, I can't seem to find the focus to just sit down and do it. It seems overwhelming at this point, all those characters and story lines, and I tend to distract when I'm feeling overwhelmed.
Not that writing here is counterproductive in any way. Writing in general, especially here and in my journal, is so much more helpful to me than a therapist. I can gather my thoughts together instead of having to explain the same old story yet another time for someone else to therapize. All that stuff about not being listened to and feeling powerless as a child doesn't apply when I'm writing, even if I'm the only one listening. So, I will go to Amazon.com today and order the "Arvo Part" CD and I promise to sit down at my laptop and work on my book.
About the D, I've promised to limit myself to moderatation only on the weekends and major holidays. I'm finding that takes the pressure off and it's something I can commit to and live with. The discomfort of the 'next day' always strengthens my resolve to figure out a way to limit the number and size of those glasses of the stuff! As long as it's not wine, it's in moderation and I'm in bed before 1:00, I'm fine the next day.
Here's a question for you. I know we were in the midst of an intense couple of posts but I didn't realize anything was wrong. Was it because some time elapsed before I was able to respond? My husband had a double hernia operation and I was busy taking care of him so I fell behind on my posts, but what was it that upset or hurt you? This is not to criticize you at all, it just surprised me that you were obviously upset and it would help me to know if there's anything I need to be aware of in myself? The idea of my causing a friend pain isn't OK with me and something I did seemed to bring up some deep pain for you. But as we're discovering about projection, this is probably something else besides what you or I do here and now. So you wanna continue with our self- realization exploration? I think it's fascinating and very enlightening, and Dr. Bob will probably redirect us. - Barb
PS, Have you read "The Four Agreements", by Don Miguel Ruiz? Another great book I keep coming back to. If I could only keep just ONE of those four agreements for even 1 day...
> Barb,
> I just have to exhale because you responded to me. I'll read your post tomorrow in more detail. What I can respond to right now...
>
> >What kind of music is it?
> The best you can imagine. B/c when you imagine the thoughts coming to you -- they are simply within a backdrop of this beautiful man's music. *tear drop*.
>
> Tolles's stuff. Amazingly enough, when I was in a suicidal depression last year, unable to sleep, sitting up in bed holding my head, crawling sobbing and drooling on the floor to the bathroom to stare at me in the mirror, bags and wrinkles and I'M SO SAD!!!; I'd put his tape on. At 4 am I'd listen to him and again at 8 before I walked and walked for miles in the forest. breathing and trying to "be here now". It did help. really. There's just such a story behind that w/ me. and I partook in too many glasses of d. I feel sick!
> thanks for responding Barb. I needed that.
> I'll respond tomorrow. and there's nothing you should be doing with your energy BUT JUST writing.
> I might just cut you off and force you to channel your writing energies into something else. Not that I don't love to hear from you!!!!
> Love,
> KAtia
>
Posted by katia on September 14, 2003, at 14:04:11
In reply to Re: Transporting Arvo Part » katia, posted by BarbaraCat on September 14, 2003, at 13:19:24
Wonderful to hear about the books! Inspiration is sometimes hard to come by, but when it hits, act on it! (not too much tho') :-)
No, there's nothing you did. I was just feeling sensitive and overly paranoid everyone was rejecting me and avoiding me because of what happened on Friday evening. A wound from last summer was reopened it felt with a dagger. That's what is was; nothing about you. So don't worry! I just needed to check it out before I blew it up in my mind more!
>>PS, Have you read "The Four Agreements", by Don Miguel Ruiz? Another great book I keep coming back to. If I could only keep just ONE of those four agreements for even 1 day...
I think we're on a similar path...yes, a friend recommended that book to me almost a year ago. I haven't read it yet tho'. It's when I was in the intensity of two conflicts; one with my (then) boyfriend and with my (then) best friend.
I'll check it out!
I had a big " bender " as they say last night. I don't know what happened; other than after Friday, I spiralled downward and I had one glass of putrid swamp juice and then felt better - good actually. and went out and then came home and wrote my aunt a letter for two hours! didn't get to bed 'til 3. I feel wiped out today. I had very little sleep on Friday b/c I was a wreck. But as soon as I drank, I got very social and a bit "manic". It's odd how I can go from depressed state to an elevated state just by drinking.
I have to work tonight - no fun with the way I feel. I won't beat myself up over it. Rather I'm having compassion for myself as this is not easy.
I started the Lam yesterday as well. geez. I'm all screwed up. don't know what's what. I have to check my body for the rash.
take care,
Katia
Posted by katia on September 14, 2003, at 14:08:56
In reply to Re: serotonergic?, posted by fluffy on September 14, 2003, at 12:39:02
Hi Katy,
Isn't it amazing? You and I as well, have a similar history with this. I look back over the years at my journals and I just shake my head and sigh. I was so tormented and I was just trying to figure it out. I too felt it was something I needed to figure out from my past as the baggage just kept piling up. I also feel in a better space. Not necessarily b/c I'm stable, but b/c I'm finally addressing it with medication.Interesting. I take a bit of Serquel for sleep on occasion. It helps, but for me I feel slightly low the next day.
take care,
Katia> > All in all, I feel loads better than I did a year ago. I read my diary from then to check if I had teeth clenching...OH MY GOD!! I was such a wreck!! Pages and pages of how I was really normal and just having problems with my past. It never occurred to me that I had a chemical imbalance. I remember crying and crying and feeling suicidal then. Worlds away from where i am now. I have the LUXURY of complaining about side effects!
>
> I'm feeling close to normal today, and I just hope that I can get a normal night's sleep w/o the benzo.
>
> Thanks so much for the info Barb-cat. I need to bookmark that post!
>
> I hope you (and all) are well,
> Katy
Posted by fluffy on September 14, 2003, at 14:45:36
In reply to Re: serotonergic?, posted by fluffy on September 14, 2003, at 12:39:02
Hello all--
I did a search for Lithium+serotonergic and came up with some information. It seems that a couple of other people on this board reported similar side effects. And although it is rare, some people who take Li can have akathesia side effects and/or serotonin syndrome. Maybe that's what happened. Got to talk to doc tomorrow.
Katy
Posted by BarbaraCat on September 14, 2003, at 19:05:59
In reply to Re: Transporting Arvo Part » BarbaraCat, posted by katia on September 14, 2003, at 14:04:11
Hi Katia and Katy,
Katia, do you have a particular Arvo Part to recommend? Amazon has 137 hits for him!! The reviewers all seem to love his music.Ladies, I surely can relate with the upheavals you're going through. Not the same situations, but similar in how terribly uncomfortable it feels to be in that volatility and how exhausting it is to be bouncing all over the place emotionally and physically. I'm probably 2 years ahead of you with the Bipolar dx, adjusting to new meds, desperately trying to find some equilibrium and a good night's sleep. I have an insight based on my own experience that you might relate to (as we all seem to be doing for each other). One year ago around this time, I was a wreck, my nerves and emotions were all over. I was already taking lithium and I think I was taking Lam as well, but not very much.
We live in a rural area in foothills terrain and the main road can be hair raising especially in the winter when it's foggy and dark. It's really not so bad at all now that I'm used to it, but the first few winters here I was through some very tough times. I could barely drive myself and would white-knuckle it the whole way collapsing on the bed unable to do a thing but sob once I got home.
My husband and I were working a contract position at the same company and he would drive us home. Every single night I would either be curled up in fetal position moaning, or shrieking 'Slow down! I can't stand this!' and we'd have to wait by the side of the road until I calmed down enough to continue. My husband would just roll his eyes and humor me because he knows better. But reaching the home stretch was even worse because I was CONVINCED that I'd find at least one if not all of our cats' mangled furry little bodies run over by trucks and strewn all over the quiet country road we live on. Or if they weren't all accounted for within the first 30 minutes of arriving, I'd be CERTAIN that a coyote had gotten them and was out haunting the streets with a flashlight calling for them or looking in the bushes for their mangled little bodies. Life was a series of trajedies for the kid, all products of my poor fried imagination. Any time I start getting pissed at my husband, I think about all he's put up with and it brings the annoyance level down a notch or two.
Needless to say, my work suffered and that caused stress. This wasn't anything new and that level of anxiety and dread were with me off and on for many years before. But it was becoming a chronic condition that was interferring with everything. I couldn't go overnight anywhere without being tormented with thoughts of the house and cats getting blown away in a freak tornado. There were real problems as well, serious financial problems, health issues, but I knew I was overreacting to everything and could not help it. Sleep? Hah! Not without my arsenal of sleep meds, and I'd frequently wake up in a panic and not be able to get back to sleep.
I'd always clucked and smirked at those 'nervous women' it's so easy to make fun of, but here I now was, after a rather wild and crazy earlier life, a pathetic nervous woman. Benzos helped alot once I decided I needed something. I should have started taking them before this panic set in, but it was still a constant feeling of fingernails on a blackboard. Not only that but I was really constipated. Maybe not bruxism (I'd already had that one) but bad enough. A great day consisted of being able to plop little marbles into the toilet and it didn't improve much from there. A bad day was pretty damn awful. I look back on my journals as well, Katy, and am amazed that I survived such horrible misery on all levels of my being.
I was really in a precarious place, ping-ponging all over the place and felt that I would really die if I didn't find relief. When it got too bad I'd to to the emergency room, mainly to feel like I was doing something to get help, but nothing really helped that much so I was feeling very despondent that this was my lot. Alcohol was the ONLY THING that could lift me out of it immediately (and they wonder why we drink) but that became not an option with the fibromyalgia flares that were getting worse.
I was thinking about all this yesterday as I was zooming around the curves in the road - at night, enjoying the little zippy thrill feelings and thinking 'Wow, no way could I have done this last year!'. What a difference from back then when a little thrill might have sent me into orbit. Life was hell with occasional breaks, but I was exhausted from the constant strain, really depleted and out of whack in every way. There was no middle ground. I was either totally exhausted and out of it or severely agitated and despondent. Those madcap manic sprees were by this time a fond memory.
I guess I'm relating this as an 'inspirational story' to show that yes, it is possible to settle down and heal and eventually feel better. I've come so far since then, even with my Mom's death and the blips I've had since then. I'm not sure what it's due to, finding the right meds and reaching equilibrium with them, finding a great naturopath who is treating hormonal imbalances, whatever. Really, not much is all that different medicinally (well, actually, the hormonal thing has helped hugely). But something finally clicked and I'm so thankful that I made it through. This stability has persisted long enough now to trust it and, except for some bumps along the way, it is expanding. There was a reason I so anxious, not because I was weird or defective or didn't try hard enough. I was out of balance and couldn't think clearly, and now that I'm getting back in balance things are much more straightforward. I still worry about the kitties and I still have lots of problems, but the biggest thing is that I now know I can handle WHATEVER comes up, not explode, and even grow to appreciate the adventures (it's only a movie).
I think that if I had only been able go back in time to tell myself 'You're going to make it. It will take time, but have faith, it will get better!', maybe I would have relaxed a bit and not wore myself out so badly. But maybe not, because it's so hard to believe that we'll ever get better, even if God proclaimed it Him/Her self. But perhaps you can stretch a little and pretend that this is a letter to you from your future selves that you are making it and you will get better. How can I know this? Because of the commitment and heart you're putting into this journey. It's the Hero's Journey and you win no matter what and incidently, get to feeling better as well.
It's the fear that it will never get better and we won't be able to stand it that is the worst part of all of this. Isn't this so? So have faith, dear friends. I'll bet a short time from now when your meds kick in, or something else settles into place you'll view this time with amazement at how far you've come and how much you've learned, and will think you're some pretty hot mamas for persisting in the face of some Super High Intensity Training. - Barbara
Posted by katia on September 15, 2003, at 2:46:47
In reply to Arvo Part and story 4 Katy, Katia, posted by BarbaraCat on September 14, 2003, at 19:05:59
Wow Barb,
Thanks for that. I really appreciate it.
The cd I have is "alina".
It's piano and violin.I'll write more later. Simply, it's good to know you.
Katia
Posted by Dr. Bob on September 15, 2003, at 19:18:03
In reply to Arvo Part and story 4 Katy, Katia, posted by BarbaraCat on September 14, 2003, at 19:05:59
> Katia, do you have a particular Arvo Part to recommend? Amazon has 137 hits for him!! The reviewers all seem to love his music.
>
> Ladies, I surely can relate with the upheavals you're going through...Sorry to interrupt, but I'd like to redirect the discussion that doesn't have to do with medication to Psycho-Social-Babble. Here's a link:
http://www.dr-bob.org/babble/social/20030913/msgs/260402.html
Thanks,
Bob
Posted by 2lisa on September 22, 2003, at 22:51:49
In reply to Sean/andrewb and Susan. Hints for your down days!, posted by Cynthia on August 8, 1999, at 23:35:52
I have been looking for Dexedrine Spansule to purchase. Does anyone have a good website to buy this product. I have looked over the internet but I get alot of warnings and other stuff but no where to purchase this item. Can someone please reply to this at xxx
thanks
Posted by Dr. Bob on September 22, 2003, at 23:18:35
In reply to Re: Sean/andrewb and Susan. Hints for your down days! » Cynthia, posted by 2lisa on September 22, 2003, at 22:51:49
> I have been looking for Dexedrine Spansule to purchase. Does anyone have a good website to buy this product.
Just a reminder, please don't use this site to exchange information that could be used to import into the US prescription medication without a prescription:
http://www.dr-bob.org/babble/faq.html#illegal
Thanks,
Bob
Posted by ktykat91582 on September 23, 2003, at 17:26:03
In reply to for barbaracat.......lexapro and depakote » BarbaraCat, posted by joebob on July 15, 2003, at 13:23:08
i have been seeing the psydoc for over a year now and she finally told me she thinks i am either A. Bipolar or B. cyclothymia. can someone please tell me in understandable terms about these conditions...she has put me on buspirone and lexapro..will these help me?..ive been on buspirone for 1 month now and i see no change..i feel like im getting worse...i feel like theres no point in life one minute but im exstatic about my life the next.i feel like im losing my mind and watching myslef go down the drain....i have 2 babies i need to think about and i really need some help and info on these conditions....hell i might just need someone to talk to about it.....but if anyone knows how i feel and thinks they can help me please reply to me....my e-mail is ktykat91582@aol.com..thanks
Posted by JaneB on September 23, 2003, at 19:13:59
In reply to can someone please help me!!!, posted by ktykat91582 on September 23, 2003, at 17:26:03
> i have been seeing the psydoc for over a year now and she finally told me she thinks i am either A. Bipolar or B. cyclothymia. can someone please tell me in understandable terms about these conditions...she has put me on buspirone and lexapro..will these help me?..ive been on buspirone for 1 month now and i see no change..i feel like im getting worse...i feel like theres no point in life one minute but im exstatic about my life the next.i feel like im losing my mind and watching myslef go down the drain....i have 2 babies i need to think about and i really need some help and info on these conditions....hell i might just need someone to talk to about it.....but if anyone knows how i feel and thinks they can help me please reply to me....my e-mail is ktykat91582@aol.com..thanks
Could you give me a little more info. I am a grandma with 18 grandchildren and daughters who love being moms but one has need of an antidepressant. I have researched a lot and been helped by this board for 5 years. 1st question: Is Lexapro the first antidepressant you have tried?
Posted by BarbaraCat on September 23, 2003, at 22:47:15
In reply to can someone please help me!!!, posted by ktykat91582 on September 23, 2003, at 17:26:03
So sorry you're having these awful feelings. I'm bipolar and it's no picnic, but with the right meds life can be great. As you probably know, bipolar generally means a condition that is cyclic, going through the range of very high energy, impulsiveness, sometimes rage and irritability, spending sprees, not needing sleep, starting grand projects and not finishing them - that's the usual take on the manic side. The depression is the opposite, no energy, dreary, sleep alot, dead feeling, no interest in anything, feelings of worthlessness. Bipolar disorder has different levels of severity, from all out total disruption of life to moderate symptoms. The determining factor is that it is an alternating and cyclic pattern and the cycles last at least 2-3 weeks, sometimes for months, as mine did. Cyclothymia is similar to bipolar, but much less intense and cycling rapidly, sometimes up and down in the same day. The highs never reach the disordered frenzy that one sees in the severe bipolar manic phase and the lows are not as devastating, but the rapid cycling can be terribly frightening and exhausting.
Before I go into the next part and possibly alarm you, please know that you may indeed have a depressive disorder and your doctor is on the right track. Also, if what follows feels true for you, you shouldn't stop what you're taking or be afraid that you're being harmed by your meds. But you do need to act quickly with determination. Definitely do a web search on bipolar+antidepressants to understand how problematic this combination is, or on cyclothymia to arm yourself with more knowledge before seeing your psydoc. Take this post in if you want. So...
If you are bipolar, meds like Lexapro are among the worst you can be taking and it's no wonder you're not feeling better, and if anything, worse. Anything that is an SSRI, like Paxil, Prozac, Zoloft, Lexapro, has been shown to make bipolar disorder worse. Buspirone, or Wellbutrin, works on different neurotransmitters and has sometimes been used successfully, but it can be very activating without a mood stabilizer and can bring on a manic episode. In any event, this combination for a bipolar can be extremely destablizing. If your condition is in the bipolar family, it's no wonder you feel like you're climbing the walls.
I can speak from experience with this, having been diagnosed with major depressive disorder and put on every antidepressant out there. They worked at first and then stopped working and my doctor would then say 'Oh, guess you need a higher dose, or let's combine it with this different one'. I suffered unimaginably for 20 years before realizing my symptoms were bipolar, although not the classic highs/lows usually easily recognizable as bipolar. Mine were more like the opposite ends were converging into one disorder, a very agitated depression that is called bipolar mixed states.
If you have cyclothymia, you're still subject to becoming destable and swinging into the cycles by an activating medication, but not as severely. Antidepressants may be used, but only as an adjunct with primarily a mood stabilizer, such as lithium, depakote, tegretol, lamictal. I personally take lithium and lamictal which has worked beautifully for longer than other any med regimen. But there's no telling just what med is going to do the trick. Depakote has had good success with cyclothymia, but it really is trial and error. However, there is a group of meds that are indicated for these conditions and SSRI's are definitely not among them.
You really need to pursue this and if your doctor is not knowledgable about the dangers of medicating bipolar symptoms with antidepressants, I very strongly encourage you to find someone else. This is a very hot topic in the psychiatric world and I would hope she has some eventual strategy with this puzzling choice of meds rather than simply being out of the loop.
There's a book that has been extremely helpful for many of us on this board to determine if what we were experiencing was really bipolar related, and what kinds of medication should and should not be used. You can just click on the link and it will take you to Amazom.com where you can order it. Good luck and don't settle for inadequate treatment when there's definite hope for the way you're feeling. Feel free to keep in touch if you have any question. - BarbaraCat
"Why your depression isn't getting better"
> i have been seeing the psydoc for over a year now and she finally told me she thinks i am either A. Bipolar or B. cyclothymia. can someone please tell me in understandable terms about these conditions...she has put me on buspirone and lexapro..will these help me
Posted by JaneB on September 24, 2003, at 7:18:02
In reply to Re: can someone please help me!!! » ktykat91582, posted by BarbaraCat on September 23, 2003, at 22:47:15
Posted by Ponder on September 27, 2003, at 17:36:31
In reply to Re: can someone please help me!!! » ktykat91582, posted by BarbaraCat on September 23, 2003, at 22:47:15
Barbara,
Is it your position that SSRIs should be avoided altogether in bipolar patients, even if there is a stabilizer on board?
Posted by BarbaraCat on September 27, 2003, at 20:57:39
In reply to Bipolar and SSRIs » BarbaraCat, posted by Ponder on September 27, 2003, at 17:36:31
> Is it your position that SSRIs should be avoided altogether in bipolar patients, even if there is a stabilizer on board?
***Some people say that, but I think it's on a personal need basis. I was helped alot by Nortriptyline early this year and even tho' it's not an SSRI, it still acts similarly. There are a number of folks on this board who take ADs and mood stabilizers successfully. It's hard to keep track of dx's, but it seems that a good percentage of them are BP. My opinion from what I've read and personally is that one probably should take a mood stabilizer when on an SSRI whether they're BP or not.
I wonder what things would have been like if I'd added lithium to my zoloft all those years ago. My pdoc at the time kept trying to convince me, more for it's augmenting properties to prevent my meds from pooping out than for suspected BP. I recoiled in horror at the mention of lithium - that's for crazy folks and I was just severely depressed! Silly me. I might have gone happily along with the combo as others have done instead of ending up in the psych unit and one mixed state after another followed from there. The lack of mood stabilizer probably destabilized me into a more severe BP condition than I would have had otherwise.
I don't know why a TCA would work so differently from an SSRI-type med, but it does for me. I was taking Remeron for a few months as I was ramping up with lithium and Lamictal. I still felt very mixed statey, on the edge of doom all the time. It wasn't until I jettisoned the Rem that I started feeling OK. This was on the recommendation of another babbler who had gone through a similar experience. I can't take SSRI's any longer, even tho' they worked pretty well for awhile. I also wonder about Wellbutrin since it's not an SSRI.
If you haven't gone to this website, by all means do so. It has tons of information in it and one article goes thoroughly into ADs and bipolar. You may need to navigate to 'Home' to get the intro page:
http://www.psycheducation.org/depression/frameset.html
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