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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by kotsunega on May 7, 2004, at 18:24:18
Four years ago I was chronically manic with psychotic features and started on 20mg daily of Zyprexa. It was the first thing that ever worked to control my mania. I have taken that dose ever since. I also have inattentive ADD.
Well, in February of this year I had gastric bypass surgery and I have now lost about 30 lbs. I find my inattention at work is increasing. The Ritalin I take for it is not really effective for me like it used to be.
I'm trying to sort out my medication dilemma and I'm wondering if too much Zyprexa, now that I've lost some weight, is exacerbating my inattentive condition or if it is just that the Ritalin pooped out. I've tried Adderall and Dexedrine, and neither one worked with Zyprexa (they did work for me many years ago before I became manic and was put on Zyprexa.
I know Dopamine plays a roll in both mania and ADD and Zyprexa has dopamine antagonist properties (good for the mania; bad for the ADD). Is it possible if I reduce my Zyprexa dose that I could find a happy medium where my mania would be reasonably controlled, but my inattention problems would be reduced?
Thanks for any thoughts.
K
Posted by HappyGirl on May 7, 2004, at 22:53:58
In reply to Need Zyprexa advice, posted by kotsunega on May 7, 2004, at 18:24:18
Hi:
20 mg. Zyprexa is quite a 'heavy' dosage, if you have Bipolar. However, it sounds to me like you have so to speak, 'Shizoaffective Bipolar disorder' that means your Bp is more close/resemble to Shizophrenia form of Bipolar. In that case, 20 mg. Zyprexa is appropriate dosage.
In regard to 'inattentive Add,' ... and then asking what form of med. for this condition. In my suggestion, either Wellbutrin SR/XL(currently) or Strattra might be a good choise. The W.B. is a sort 'stimulant,' for that reason, you may need one more med. to counteract S.E. from taking W.B. In my case(BP II with ultra rapid cycler), Serzone/Nefadozone makes things/S.E. mellow out. However, some saying, Strattra is better than W.B., because this med. has a good property of anti-depressant, although it's made for ADD.
Those two meds. and another 'stimulant' is 'provigil'(sp?), you could look for. However, if your 'mania' is quite 'severe form' such as 'psychotic' and 'delutional' type, then you need to search for other 'stimulant' for your ADD.
H.G.
Posted by cybercafe on May 8, 2004, at 5:06:26
In reply to Need Zyprexa advice, posted by kotsunega on May 7, 2004, at 18:24:18
> Four years ago I was chronically manic with psychotic features and started on 20mg daily of Zyprexa. It was the first thing that ever worked to control my mania. I have taken that dose ever since. I also have inattentive ADD.
>
> Well, in February of this year I had gastric bypass surgery and I have now lost about 30 lbs. I find my inattention at work is increasing. The Ritalin I take for it is not really effective for me like it used to be.
>
> I'm trying to sort out my medication dilemma and I'm wondering if too much Zyprexa, now that I've lost some weight, is exacerbating my inattentive condition or if it is just that the Ritalin pooped out. I've tried Adderall and Dexedrine, and neither one worked with Zyprexa (they did work for me many years ago before I became manic and was put on Zyprexa.
>
> I know Dopamine plays a roll in both mania and ADD and Zyprexa has dopamine antagonist properties (good for the mania; bad for the ADD). Is it possible if I reduce my Zyprexa dose that I could find a happy medium where my mania would be reasonably controlled, but my inattention problems would be reduced?
>
> Thanks for any thoughts.
>
> Kall i can say is i hope you are wiser than most, my friend, to show great patience, decrease and increase your medications independently and very slowly.... and let your doctor know what you are doing in 90% of cases
Posted by Sebastian on May 9, 2004, at 9:54:08
In reply to Need Zyprexa advice, posted by kotsunega on May 7, 2004, at 18:24:18
You might do ok on a lower dose of zyprexa now that you have the condition under control. Try lowing the dose to 15 mg. I've been taking 10 mg zyprexa for the last 5 or so years. Just recently I lowered the dose to 7.5, which seems to work better than the 10 mg now.
This is the end of the thread.
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