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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by TheMeanReds on March 1, 2007, at 12:08:07
I'm on 2.5mg of Abilify and it's day 2. I feel like time is going by very slowly. I do chores that seem like they would take ages, but only a few minutes or so pass. I've been awake for only 3 hours, but it feels like twice as long. Is this a speed like effect? I don't think it's a tranquilizing effect, because I've been on tranqs for years.
Its odd but the drug does have anti depressant qualities, I think. Maybe its just my bipolar II being in an 'equal' state?
Anyone else experience odd time lapses on Abilify?
Posted by med_empowered on March 1, 2007, at 12:23:50
In reply to Abilify + Time, posted by TheMeanReds on March 1, 2007, at 12:08:07
I think with a lot of neuroleptics low-doses tend to speed up reaction time a little bit--even haldol does this--which would indicate some sort of dopamine agonism and possible antidepressant effect. With Abilify, which is very high potency (@ 30mgs/day, 90+% of D2 receptors are occupied--if it weren't for the partial agonism, that would cause major EPS), I think its particularly pronounced b/c of the partial agonism and the effects on serotonin.
WHat else are you taking?If you've been taking other antipsychotics, even at low doses, you may now have a lot more dopamine hanging around than before...maybe thats part of it?
Posted by yxibow on March 1, 2007, at 18:48:21
In reply to Re: Abilify + Time, posted by med_empowered on March 1, 2007, at 12:23:50
> I think with a lot of neuroleptics low-doses tend to speed up reaction time a little bit--even haldol does this--which would indicate some sort of dopamine agonism and possible antidepressant effect. With Abilify, which is very high potency (@ 30mgs/day, 90+% of D2 receptors are occupied--if it weren't for the partial agonism, that would cause major EPS),
Oh I beg to differ on the major EPS part... Abilify causes just about the same amount of akathisia as Geodon does in me, unfortunately. I was hoping for something different. But then I have an affective disorder.
Posted by linkadge on March 1, 2007, at 20:18:04
In reply to Re: Abilify + Time » med_empowered, posted by yxibow on March 1, 2007, at 18:48:21
I have had distortions of time when taking many agents that block 5-ht2a. I know that LSD (which interacts with 5-ht2a) can affect the preception of time.
I think that this may be a side effect of drugs acting at 5-ht2a.
Linkadge
Posted by TheMeanReds on March 2, 2007, at 11:31:46
In reply to Re: Abilify + Time, posted by med_empowered on March 1, 2007, at 12:23:50
I'm also on lamictal 200 mgs. But I'm lowering my dose to 50mgs. I heard that when a person reaches a theraputic dose, that the person should think about stopping at that dose. I know 50mgs had been fine...but upping to 200 makes anxiety alot higher, and I think I tend to eat more (the 2 side effects I dislike the most). So that said, I'm on 100 seroquel/night, 2mg klnopin/day, 1mg of Xanax/day when I know I'm going to be a nervous wreck (a new drug to me as of a few days ago), and quasense so my girly hormones wont mess with my Bipolar II.
I heard Lamictal is the best BP drug to augment with as well. I'm not savvy on the scientific terms as alot of people on the board are, so any responses in layman's terms would be greatly appreciated.
Thank you =)
Posted by TheMeanReds on March 2, 2007, at 11:40:24
In reply to Re: Abilify + Time, posted by linkadge on March 1, 2007, at 20:18:04
> I have had distortions of time when taking many agents that block 5-ht2a. I know that LSD (which interacts with 5-ht2a) can affect the preception of time.
>
> I think that this may be a side effect of drugs acting at 5-ht2a.
>
> LinkadgeYeah I agree LSD does distort time, I'm not sure what LSD doesnt distort though. Imagine if LSD were prescribed for mental illness nowadays. This board would be full of conversations about LSD side effects =)
This is the end of the thread.
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