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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by linkadge on January 30, 2018, at 16:45:52
I switched from mirtazapine to nortriptyline about year ago.
I am not finding nortriptyline as beneficial for sleep. Last night, for example, it seems like I woke up no less than 30 times.
I was able to fall back asleep quickly, but the effect is taking its toll.
I'm going to see if I can switch back to mirtazapine.
Linkadge
Posted by SLS on January 30, 2018, at 21:13:23
In reply to nortriptyline - microwaking, posted by linkadge on January 30, 2018, at 16:45:52
> I switched from mirtazapine to nortriptyline about year ago.
>
> I am not finding nortriptyline as beneficial for sleep. Last night, for example, it seems like I woke up no less than 30 times.
>
> I was able to fall back asleep quickly, but the effect is taking its toll.
>
> I'm going to see if I can switch back to mirtazapine.
>
> LinkadgeI thought you were being helped by nortriptyline.
Why not just add a small amount of mirtazapine to the nortriptyline to act as a sleep aid rather than make a switch?
- Scott
Posted by linkadge on January 31, 2018, at 16:11:00
In reply to Re: nortriptyline - microwaking, posted by SLS on January 30, 2018, at 21:13:23
I wanted to switch from mirtazapine to nortriptyline primarily as I thought it may help me with sleep, with less collateral effect on next day energy.
The problem is that the nortriptyline doesn't appear near as effective for sleep. My sleep onset is worse, maintainance is worse and I still get early morning wakenings.
I'm just finding it too stimulating.
Linkadge
Posted by SLS on January 31, 2018, at 17:23:41
In reply to Re: nortriptyline - microwaking » SLS, posted by linkadge on January 31, 2018, at 16:11:00
> I wanted to switch from mirtazapine to nortriptyline primarily as I thought it may help me with sleep, with less collateral effect on next day energy.
>
> The problem is that the nortriptyline doesn't appear near as effective for sleep. My sleep onset is worse, maintainance is worse and I still get early morning wakenings.
>
> I'm just finding it too stimulating.
>
> Linkadge
I've never found nortriptyline to be sedating. It's not like amitriptyline.I thought nortriptyline was helping for depression. That's why I suggested the combination. Just throwing it out there... Higher dosages of mirtazapine and nortriptyline may work synergistically to increase NE along with the 5-HT2a/c and 5-HT3 receptor blockade.
Perhaps you can make the switch from nortriptyline to mirtazapine first and evaluate your level of deepression. If you see that your depression gets worse, you might then restart nortriptyline and reevaluate depression and sleep continuity.
- Scott
Posted by SLS on January 31, 2018, at 17:29:39
In reply to Re: nortriptyline - microwaking » SLS, posted by linkadge on January 31, 2018, at 16:11:00
> I'm just finding it too stimulating.
I see. I overlooked this.
I have to ask. In what ways is nortriptyline too stimulating? Is it just sleep, or does it also affect you negatively during the day?
- Scott
Posted by linkadge on January 31, 2018, at 19:43:38
In reply to Re: nortriptyline - microwaking » linkadge, posted by SLS on January 31, 2018, at 17:29:39
Yeah, its not a clear effect.
It's initially making me tired, but then I wake up frequently throughout the night. It seems to be disrupting the continuity.
Linkadge
This is the end of the thread.
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