Psycho-Babble Medication Thread 278321

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Zyprexa for severe depression?

Posted by Lazarus on November 10, 2003, at 17:52:32

My pdoc has diagnosed me as having profound depression. Instead of prescribing an antidepressant he told me to increase my dosage of Zyprexa from 1.25 mg to 5 mg, nightly. Has anyone else experienced this? I have bipolar disorder.

Lazarus

 

Re: Zyprexa for severe depression?

Posted by Bananafish on November 11, 2003, at 9:45:05

In reply to Zyprexa for severe depression?, posted by Lazarus on November 10, 2003, at 17:52:32

I also have Bipolar, and have taken Zyprexa to bring manic episodes under control, but never for depression. It is a very sedating drug, and I tend to think it would worsen depression. Are you taking any antidepressants? I think antidepressants and mood stabilizers are what you probably need.

 

Re: Zyprexa for severe depression? » Bananafish

Posted by ace on November 11, 2003, at 20:24:02

In reply to Re: Zyprexa for severe depression?, posted by Bananafish on November 11, 2003, at 9:45:05

> I also have Bipolar, and have taken Zyprexa to bring manic episodes under control, but never for depression. It is a very sedating drug, and I tend to think it would worsen depression.

I have to disagree...I believe it usually makes depression better, esp if taken with another serotonergic AD. For some, it is a stand alone AD like Risperidone (this drug can really work great for depression). I agree, it is sedating, but this usually wears off. But, I have seen some wonderful responses from Zyprexa- for depression, OCD, bipolar etc...

Are you taking any antidepressants? I think antidepressants and mood stabilizers are what you probably need.

 

Re: Zyprexa for severe depression?

Posted by Lazarus on November 12, 2003, at 18:49:47

In reply to Re: Zyprexa for severe depression? » Bananafish, posted by ace on November 11, 2003, at 20:24:02


> Are you taking any antidepressants? I think antidepressants and mood stabilizers are what you probably need.

I took Wellbutrin for many years, then replaced it with Strattera last Spring. I also take lithium.

My pdoc wants me off the Strattera and the Abilify and to take just the Zyprexa, 5mg. He says that this will arrest the depression. But, I feel that the Zyprexa is making me more and more depressed. I'm drowning, I can't breathe and the world has turned eerily silent. I feel hopelessly depressed.

Lazarus

 

Re: Zyprexa for severe depression?

Posted by jamesprice on November 14, 2003, at 11:55:13

In reply to Re: Zyprexa for severe depression?, posted by Lazarus on November 12, 2003, at 18:49:47

Zyprexa helped for 1 day with the depression but after that it wore off.

I don't think it's really shown in the studies to help with depression much, only mania.


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