![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 16 of 16. This is the beginning of the thread.
Posted by Shy_Girl on May 21, 2005, at 21:12:11
Hmmm...it's wierd, I think I'm feeling more stable now...not sure if it is the 50mg Celexa + placebo response or because of a change in thinking??
Anyways, I was on Celexa since Feb. and up until a week or so, I was still pretty up and down all the time. Did it just take a long time for the Celexa + placebo response to work for me? (I add in placebo response because I think this response is pretty significant in pysch meds...something like 30%) Is this typical of people with borderline personality dx?...that we need to be on an SSRI for longer and at higher doses? Or, am I premature in making the assumption that I'm stable after only about a week?
Posted by cybercafe on May 21, 2005, at 21:17:31
In reply to Think I feeling more stable...is it the Celexa?, posted by Shy_Girl on May 21, 2005, at 21:12:11
> Hmmm...it's wierd, I think I'm feeling more stable now...not sure if it is the 50mg Celexa + placebo response or because of a change in thinking??
>
> Anyways, I was on Celexa since Feb. and up until a week or so, I was still pretty up and down all the time. Did it just take a long time for the Celexa + placebo response to work for me? (I add in placebo response because I think this response is pretty significant in pysch meds...something like 30%) Is this typical of people with borderline personality dx?...that we need to be on an SSRI for longer and at higher doses? Or, am I premature in making the assumption that I'm stable after only about a week?
i was told SSRIs (esp Celexa) have SOME mood stabilizing properties
Posted by Shy_Girl on May 21, 2005, at 21:41:08
In reply to Re: Think I feeling more stable...is it the Celexa?, posted by cybercafe on May 21, 2005, at 21:17:31
> i was told SSRIs (esp Celexa) have SOME mood stabilizing properties
Really? Why esp. Celexa? Is it true for all SSRIs? Does the mood stablizing properties appear only at higher dosages? I haven't been on the 50mg for too long yet...maybe 2 weeks.
Or maybe I am coping better because I know I cannot see my p-doc for a while? (she's on maternity leave)
Posted by Shy_Girl on May 21, 2005, at 21:49:31
In reply to Re: Think I feeling more stable...is it the Celexa? » cybercafe, posted by Shy_Girl on May 21, 2005, at 21:41:08
I have a history of pretty sudden and intense suicidal urges and just "dysphoria"...someone who had a BPD said that taking zyprexa helped her with those episodes greatly.
Should I inquire about this? So far no doctors have ever suggested anything other than an SSRI for me (well except 5 doses of propranolol). How should I approach my GP (whom I haven't seen in years!) about this? Like I mentioned before, I have no p-doc right now.
Posted by Nixon on May 21, 2005, at 21:58:33
In reply to Re: Should I ask about a med for crises?, posted by Shy_Girl on May 21, 2005, at 21:49:31
> I have a history of pretty sudden and intense suicidal urges and just "dysphoria"...someone who had a BPD said that taking zyprexa helped her with those episodes greatly.
>
> Should I inquire about this? So far no doctors have ever suggested anything other than an SSRI for me (well except 5 doses of propranolol). How should I approach my GP (whom I haven't seen in years!) about this? Like I mentioned before, I have no p-doc right now.Hi,
You have mentioned mood issues in your posts. You may want to inquire about taking a low dose of an AED mood stabilizer such as Depakote or Trileptal. They may lessen these sudden intense urges. Zyprexa as your friend mentioned may be helpful.
Posted by Shy_Girl on May 21, 2005, at 22:10:50
In reply to Re: Should I ask about a med for crises? » Shy_Girl, posted by Nixon on May 21, 2005, at 21:58:33
Would a mood stabilizer such as Depakote or Trileptal help with my sometimes very intense and maybe even paranoid rages? Sometimes I sort of "lose it" and can became quite irrational. That is mostly what I am afraid of...killing myself in a fit of rage or despair. I don't really have any problems with my "highs"...they are quite enjoyable, too bad they don't last longer.
Would a mood stablizer like an AED even out my mood so that I no longer experience my passionate "highs"...if so, not sure if it is worth it. :-) I only want to get rid of the horrible depressive and rageful episodes.
Posted by Nixon on May 21, 2005, at 22:18:00
In reply to Re: Should I ask about a med for crises?, posted by Shy_Girl on May 21, 2005, at 22:10:50
> Would a mood stabilizer such as Depakote or Trileptal help with my sometimes very intense and maybe even paranoid rages? Sometimes I sort of "lose it" and can became quite irrational. That is mostly what I am afraid of...killing myself in a fit of rage or despair. I don't really have any problems with my "highs"...they are quite enjoyable, too bad they don't last longer.
>
> Would a mood stablizer like an AED even out my mood so that I no longer experience my passionate "highs"...if so, not sure if it is worth it. :-) I only want to get rid of the horrible depressive and rageful episodes.Yes they MAY help you but there is no definite answer for that until you try. I can tell you there is PROBABLY just as much of a chance of losing your nice highs and staying depressed if you started Zyprexa instead.
Posted by Shy_Girl on May 21, 2005, at 22:32:41
In reply to Re: Should I ask about a med for crises?, posted by Nixon on May 21, 2005, at 22:18:00
> I can tell you there is PROBABLY just as much of a chance of losing your nice highs and staying depressed if you started Zyprexa instead.
Oh, I forgot to mention...I don't want to take something like Zyprexa on a daily basis. I'm thinking of using it (or something else) for my crises only...low dose, as needed basis.
Posted by Nixon on May 21, 2005, at 22:40:02
In reply to Re: Should I ask about a med for crises?, posted by Shy_Girl on May 21, 2005, at 22:32:41
> > I can tell you there is PROBABLY just as much of a chance of losing your nice highs and staying depressed if you started Zyprexa instead.
>
> Oh, I forgot to mention...I don't want to take something like Zyprexa on a daily basis. I'm thinking of using it (or something else) for my crises only...low dose, as needed basis.
>
>
Ok. It shoulds be noted that Depakote is effective for Acute Mania. You may see help after a few days. I am not certain Zyprexa will immediately pull you out of a swing. A Benzo would have an immediate effect though it may just calm you down. I can't see Zyprexa making you feel less depressed while calming mania immediately. But anything can happen.
Posted by Shy_Girl on May 21, 2005, at 22:58:01
In reply to Re: Should I ask about a med for crises?, posted by Nixon on May 21, 2005, at 22:40:02
I don't have mania though. I have social anxiety and a BPD. I've never been manic and I'm not bipolar. It is unlikely I will get meds other than an SSRI. Perhaps I should concentrate on CBT?
I'm very curious about where one read that SSRIs have mood stabilizing effects though.
Posted by Maxime on May 21, 2005, at 23:19:04
In reply to Think I feeling more stable...is it the Celexa?, posted by Shy_Girl on May 21, 2005, at 21:12:11
Hi Shy Girl :-)
I'm glad to hear you are feeling more stable. I doubt it's the Celexa since you have been taking it since February. Did you start taking anything else, any vitamins or the like?
I hope you continue to feel good.
Love,
Maxime
> Hmmm...it's wierd, I think I'm feeling more stable now...not sure if it is the 50mg Celexa + placebo response or because of a change in thinking??
>
> Anyways, I was on Celexa since Feb. and up until a week or so, I was still pretty up and down all the time. Did it just take a long time for the Celexa + placebo response to work for me? (I add in placebo response because I think this response is pretty significant in pysch meds...something like 30%) Is this typical of people with borderline personality dx?...that we need to be on an SSRI for longer and at higher doses? Or, am I premature in making the assumption that I'm stable after only about a week?
Posted by Dinah on May 22, 2005, at 9:17:21
In reply to Re: Should I ask about a med for crises?, posted by Shy_Girl on May 21, 2005, at 22:30:24
I've found low dose Risperdal, as needed, worked for my meltdowns.
The trick is that it takes a couple of hours for its tranquilizing effects to take hold, and in that time I need to hold on tight and not act on any impulses.
I imagine Zyprexa might be the same.
Antipsychotics used to be known as major tranquilizers or sedatives or something, and I thinkt that's very apt.
I also found low dose Depakote helped with mood stability, but higher doses (for migraines) are making me feel too thick.
Posted by Shy_Girl on May 22, 2005, at 13:34:28
In reply to Re: Think I feeling more stable...is it the Celexa, posted by Maxime on May 21, 2005, at 23:19:04
>I doubt it's the Celexa since you have been taking it since February. Did you start taking anything else, any vitamins or the like?
Nope, nothing else...just been on the 50mg for about two weeks.
> I hope you continue to feel good.Me too.
Thanks Maxime
Shy_Girl
Posted by Phillipa on May 22, 2005, at 18:32:33
In reply to Re: Think I feeling more stable...is it the Celexa, posted by Shy_Girl on May 22, 2005, at 13:34:28
Shy Girl, doesn't your pdoc have someone covering for her while she's out on leave? Fondly, Phillipa
Posted by Shy_Girl on May 22, 2005, at 18:41:54
In reply to Re: Think I feeling more stable...is it the Celexa, posted by Phillipa on May 22, 2005, at 18:32:33
> Shy Girl, doesn't your pdoc have someone covering for her while she's out on leave? Fondly, Phillipa
Nope...I'm supposed to see my family physician...but I haven't seen her in years and she's on vacation right now.
I went to a walk-in-clinic and the doctor there couldn't do anything for me.
I'm ok right now so I guess it doesn't really matter.
Thanks
Posted by cybercafe on May 24, 2005, at 3:15:34
In reply to Re: Think I feeling more stable...is it the Celexa? » cybercafe, posted by Shy_Girl on May 21, 2005, at 21:41:08
> > i was told SSRIs (esp Celexa) have SOME mood stabilizing properties
>
> Really? Why esp. Celexa? Is it true for all SSRIs? Does the mood stablizing properties appear only at higher dosages? I haven't been on the 50mg for too long yet...maybe 2 weeks.
>
> Or maybe I am coping better because I know I cannot see my p-doc for a while? (she's on maternity leave)
>
>Honest answer: this is something I posted about perhaps 2 years ago. A more comprehensive answer can be found in the archives.
As I understand it, serotonin has mood stabilizing properties. Norepenephrine tends to cause cycling. In general. Perhaps it is because serotonin causes a balance with, or lowering, of dopamine? I'm not sure.
But it's definately something I felt. Especially more in the more selective SSRIs.
Still, I don't think it compares to a strong mood stabilizer like an antipsychotic.
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.