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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 14 of 14. This is the beginning of the thread.
Posted by sisss42 on April 24, 2007, at 23:51:59
Can anyone tell me what chemical is responsible for the marked antidepressant effect I feel when I take this drug so far I have found that
XANAX Tablets contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.
The chemical name of alprazolam is 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-I] [1,4] benzodiazepine.
Regards
Sis
Posted by rjlockhart on April 25, 2007, at 0:01:09
In reply to antidepressant effects and xanax, posted by sisss42 on April 24, 2007, at 23:51:59
I dont know what.
Definelty someone here does, i take xanax, sometimes it depends on the situation im in.
But defintly xanax is antidepressant out of all of them. Benzodiazepines.
Posted by sisss42 on April 25, 2007, at 6:49:56
In reply to Re: antidepressant effects and xanax, posted by rjlockhart on April 25, 2007, at 0:01:09
thanks for replying not on xanax at the moment, have been in the past I am hoping to find out what is responsible as it may point me in the right direction as have been on lots of ADs and have never experienced the uplift in mood that xanax gives me for a while between doses
Posted by Phillipa on April 25, 2007, at 11:29:29
In reply to Re: antidepressant effects and xanax » rjlockhart, posted by sisss42 on April 25, 2007, at 6:49:56
Well I know that of all the benzos it does have a small ad property. What was your dose and I'm not clear by what you mean between doses? Of the xanax or antidepressants? Love Phillipa
Posted by sisss42 on April 25, 2007, at 16:04:02
In reply to Re: antidepressant effects and xanax » sisss42, posted by Phillipa on April 25, 2007, at 11:29:29
Hi Phillipa
My response to xanax has been a marked not a small ad effect, after taking it my mood lifts dramatically for a while in between doses of (5mg If I remember correctly) twice daily, I know that is a short acting benzo, I was on it for months until I developed a tolerance, my pdoc did not want to increase the dose so we switched to Clonazapam amd then Diazapam but only the Xanax has the ad effect for me, hope this is clearer.
Regards
Sis
Posted by jealibeanz on April 25, 2007, at 16:06:01
In reply to Re: antidepressant effects and xanax » sisss42, posted by Phillipa on April 25, 2007, at 11:29:29
I can't tell you why Xanax help with depression. I wonder the same thing, but it does help me. While Klonopin caused depression.
I can't find an AD I tolerate and I have anxiety. If I told my doctor I wanted to stay on Xanax long term because it made me happy, I think it would be taken away (oh wait, it already has, with the substitution of XR, which I feel acts like a combo of Xanax IR and Klonopin... without relieving axiety, thus, it causes a little depression I feel.)
Posted by Phillipa on April 25, 2007, at 19:56:08
In reply to Re: antidepressant effects and xanax » Phillipa, posted by jealibeanz on April 25, 2007, at 16:06:01
Jelly same here. I hated the long-acting and klonopin was the pits for me. Now the short acting again I merely asked for it yesterday and said do you trust me not to abuse it? She said of course. So everything is back on course. If I knew chemistry and all the deep stuff maybe I could figure out the ad properties of xanax? But I don't Love Phillipa
Posted by jealibeanz on April 26, 2007, at 4:15:28
In reply to Re: antidepressant effects and xanax » jealibeanz, posted by Phillipa on April 25, 2007, at 19:56:08
The whole "abusing Xanax" thing bothers me. I realize that there's reason for doctors to be concerned if the patient has an addictive personality and tends to take the medication in larger than prescribed quantities per day... but it's a prescription drug.
If someone takes more than prescribed they run out before the next prescription. It's not like we have unlimited quantities and go out and get more without a doctor's authorization. They do have some control over this... that's why it's called a "controlled" drug.
If you have someone who's asking for Xanax, in my opinion, you have a good situation. They are seeking the help and monitoring of a professional. This is safer than someone who doesn't seek help and instead chooses to drink alcohol and or use illicit drugs excessively... many who go that route probably do have some sort of mood disorder. Doctors should be made of aware of the fact that treating someone's anxiety or depression helps to make them a healthier person overall who can make better lifestyle choices and positively contribute to and influence society.
Anxiety and depression prevalence rates keep rising... especially among college students... it's not a good thing when the youth of the country is inflicted with such detrimental disease. It's going to show up in the workforce and entire functioning of this country and our government if we aren't properly treated.
Posted by sisss42 on April 26, 2007, at 4:44:48
In reply to antidepressant effects and xanax, posted by sisss42 on April 24, 2007, at 23:51:59
Can anyone tell me what chemical is responsible for the marked antidepressant effect I feel when I take this drug so far I have found that
XANAX Tablets contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.
The chemical name of alprazolam is 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-I] [1,4] benzodiazepine.
Regards
Sis
Posted by sisss42 on April 26, 2007, at 5:09:26
In reply to Chemistry, antidepressant effects and xanax, posted by sisss42 on April 26, 2007, at 4:44:48
>
As we are sort of going off course with this thread I have added Chemistry to the subject you never know we might find a chemist out there, thinking about it wasn't there someone called chemist who used to post here regularly? thanks for all your responses.
sisCan anyone tell me what chemical is responsible for the marked antidepressant effect I feel when I take this drug so far I have found that
>
> XANAX Tablets contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.
>
> The chemical name of alprazolam is 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-I] [1,4] benzodiazepine.
>
> Regards
> Sis
>
>
>
Posted by Larry Hoover on April 26, 2007, at 8:12:09
In reply to Chemistry, antidepressant effects and xanax, posted by sisss42 on April 26, 2007, at 4:44:48
> Can anyone tell me what chemical is responsible for the marked antidepressant effect I feel when I take this drug so far I have found that
>
> XANAX Tablets contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.
>
> The chemical name of alprazolam is 8-chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-I] [1,4] benzodiazepine.
>
> Regards
> SisYou've already answered yourself, although you may not have realized that. The chemical is called alprazolam when it is being discussed by non-chemists, or as 8-chloro-1-methyl-6-phenyl-4H-
1,2,4-triazolo(4,3-a)(1,4)benzodiazepine when it is being discussed by chemists. Alprazolam is the trivial, or common name, for the specific chemical you're thinking about. The other one is the systematic, or IUPAC name, for the same molecule. The systematic name you provided is a little out of date, if anyone notices subtle differences.Here's a picture of the chemical: http://en.wikipedia.org/wiki/Alprazolam
If you look at that diagram, which is meant to represent the layout of atoms within the molecule (chemical), you'll appreciate that there are specific sequences and arrangements of individual atoms. Every alprazolam molecule has this arrangement. Nitrogen atoms and chlorine are represented by the N and Cl symbols, respectively. To make the structure less confusing, hydrogen atoms are left off entirely (13 of those), and everywhere else, at the end of any line that has no letter symbol, there is a carbon atom (17 altogether). The diagram is further simplified by being a two-dimensional representation of a three-dimensional object.
It is a very complicated molecule. It is a single chemical, however. And only that specific chemical has those specific properties (whatever they might be).
Of all the benzodiazepine drugs, alprazolam is most often associated with an antidepressant effect. As far as I know, nobody has ever shown why that is the case. It is used, however, as an antidepressant augmentative alongside antidepressant medication.
I cannot suggest any substitute for that drug, if you cannot obtain that specific one from your treating physicians.
Lar
Posted by sisss42 on April 26, 2007, at 16:13:06
In reply to Re: Chemistry, antidepressant effects and xanax » sisss42, posted by Larry Hoover on April 26, 2007, at 8:12:09
> > Can anyone tell me what chemical is responsible for the marked antidepressant effect I feel when I take this drug so far I have found that
> >
> > XANAX Tablets contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.
> >
> > The chemical name of alprazolam is 8-chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-I] [1,4] benzodiazepine.
> >
> > Regards
> > Sis
>
> You've already answered yourself, although you may not have realized that. The chemical is called alprazolam when it is being discussed by non-chemists, or as 8-chloro-1-methyl-6-phenyl-4H-
> 1,2,4-triazolo(4,3-a)(1,4)benzodiazepine when it is being discussed by chemists. Alprazolam is the trivial, or common name, for the specific chemical you're thinking about. The other one is the systematic, or IUPAC name, for the same molecule. The systematic name you provided is a little out of date, if anyone notices subtle differences.
>
> Here's a picture of the chemical: http://en.wikipedia.org/wiki/Alprazolam
>
> If you look at that diagram, which is meant to represent the layout of atoms within the molecule (chemical), you'll appreciate that there are specific sequences and arrangements of individual atoms. Every alprazolam molecule has this arrangement. Nitrogen atoms and chlorine are represented by the N and Cl symbols, respectively. To make the structure less confusing, hydrogen atoms are left off entirely (13 of those), and everywhere else, at the end of any line that has no letter symbol, there is a carbon atom (17 altogether). The diagram is further simplified by being a two-dimensional representation of a three-dimensional object.
>
> It is a very complicated molecule. It is a single chemical, however. And only that specific chemical has those specific properties (whatever they might be).
>
> Of all the benzodiazepine drugs, alprazolam is most often associated with an antidepressant effect. As far as I know, nobody has ever shown why that is the case. It is used, however, as an antidepressant augmentative alongside antidepressant medication.
>
> I cannot suggest any substitute for that drug, if you cannot obtain that specific one from your treating physicians.
>
> Lar
>
> Thank you for the link, very interesting. I was hoping to find the reason for my ad response,but seems like I'm looking for a needle in a haystack.
Have been on many antidepressants as well as Zyprexa and ECT in the past and only ever achieve a partial response. At present am on Effexor and (Diazapam,weaning off slowly) have just added Avanza(Remeron)to the mix in the hope that it will help with my (label) treatment resistant depression.Best wishes from OZ
Sis
Posted by jealibeanz on April 26, 2007, at 16:43:42
In reply to Re: Chemistry, antidepressant effects and xanax » Larry Hoover, posted by sisss42 on April 26, 2007, at 16:13:06
Sis-
So you aren't taking Xanax right now? Or are taking diazepam daily and Xanax PRN?
Posted by sisss42 on April 26, 2007, at 20:17:38
In reply to Re: Chemistry, antidepressant effects and xanax » sisss42, posted by jealibeanz on April 26, 2007, at 16:43:42
> Sis-
>
> So you aren't taking Xanax right now? Or are taking diazepam daily and Xanax PRN?Hi
Not taking xanax now and am trying to get off Benzo's altogether
sis
This is the end of the thread.
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