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Re: Duloxetine Questions

Posted by SLS on May 13, 2001, at 11:12:09

In reply to Duloxetine Questions, posted by Neal on May 13, 2001, at 1:58:51

Hi Neal.

> Lilly at the present time is already heavily investing their big bucks in what they hope is the next blockbuster antidepressant, duloxetine.
>
> So, what is it, how are the trials coming, is it another SSRI?


Someone mentioned this in a previous thread. This is news to me.

Duloxetine is a SNRI (serotonin-norepinephrine reuptake inhibitor). It inhibits the reuptake of both serotonin and norepinephrine.

When I first heard about duloxetine a number of years ago, I was looking forward to seeing its development. However, my unreliable memory recalls encountering something on Medline that gave me the impression that it is not a very promising compound for treating depression. I hope they were wrong.


- Scott

 

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