Posted by shelliR on May 14, 2001, at 12:18:46
In reply to Re: Duloxetine Questions/late-stage data, posted by SLS on May 14, 2001, at 7:52:28
> Hi.
>
> From the news brief:
>
> "The company said that 50% of duloxetine-treated patients achieved remission of depression symptoms, versus 29.5% of patients receiving placebo."
>
> I don't want to rain on anyone's parade, and I don't doubt that duloxetine will effectively treat some people who have not responded to any other drug, but 50% versus 30% sucks. Well, I should say that 50% sucks if the same criteria were used for this study that have been used in the past for the same protocols.
>
> I would like to see duloxetine approved. The more tools that are available to me, the greater the likelihood that I will find an effective treatment and start a new life in the world of the living.
>
> What do others think of 50% duloxetine versus 30% placebo?
>
>
> - ScottScott, there are two things about this study that I find even more interesting than the 50% vs 30% duloxetine vs placebo results.
1) In addition to testing dulonetine against a placebo, they also tested it against paroxetine (paxil). Why didn't they test it against prozac!
2) Much more interesting to me: In the Reuters Medical News, they report that no figure was given for those treated with paroxetine. Why not? Leads one to believe that those treated with paxil may have had much better outcomes than with dulonetine. Just a guess. I don't get how a drug company can put out a news release on a study and omit the results of half of it.
Am I missing something, or am I just naive?
shelli
poster:shelliR
thread:62717
URL: http://www.dr-bob.org/babble/20010507/msgs/62906.html