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CAM: question about codeine and antidepressants

Posted by shelliR on September 11, 2001, at 18:03:52

Hi Cam.

Before I get to the question, some background:
I am in the unusual position of having a pdoc who is prescribing oxycontin for me, to literally get me through life until an antidepressant works. (I took hydrocodone for premenstral depression and sickness for several years, with great success, and no increase.) He is a very respected physician, but known as a non-conformist. I took nardil successfully for years and in the past almost two years, its benefit pettered out. In the past year and a half, I have tried a dozen adjuncts, then prozac, now wellbutrin. I have gotten up to 300 with no side effects, and today started very slowly to add nardil to the wellbutrin. (I am watching carefully for any signs of a hypertensive reaction)

Re the opiate part:
Once another psychiatrist told me that opiates could interfere with the success of antidepressants. When I asked my pdoc about this, he said that was the thinking in the 1970s, but not anymore. There is no interference. My depression has not abated at all in the last year, and I am beginning to wonder if there is a possiblity that there *is* some interference. I am not worried about addiction; I feel that if anti-depressant kicks in, I can slowly begin to taper off the oxycontin. And I will continue to go up on the wellbutrin once the nardil is in place. I do, however, worry some that the other psychiatrist was correct, although I cannot find any information on the internet to support it; only info on addiction, etc. Have you ever come across any mention of opiates interferring with anti-depressants, in your reading?

Thanks (in advance)
BTW, is Cam short for Cameron? Just curious.

Shelli


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poster:shelliR thread:78595
URL: http://www.dr-bob.org/babble/20010907/msgs/78595.html