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Re: Cam:antipsychotic question

Posted by gregg on December 31, 2001, at 10:52:07

In reply to Re: Cam:antipsychotic question » Chloe, posted by Cam W. on December 27, 2001, at 20:44:17

Cam,

I noticed that you say in a couple of your posts that you seldom see Seroquel used as a sole agent. I was wondering why that is. Is Seroquel not as effective as other APs (like Risperdal or Zyprexa) in treating psychosis? It would be a shame if a med with such a benign side-effect profile was a dud in treating the condition it is intended for! I am particularly interested in how effective you have found Seroquel to be in treating the psychosis in depression with psychotic features?

Thanks,
Gregg

> Chloe - I haven't heard of using melatonin successfully for EPS or TD. I have seen vitamin E used successfully...once. The Seroquel™ (quetiapine), while it may not stop these movements, will, in all probability, not worsen them (unless, by stopping the Mellaril™ - thioridazine - "unmasks" more severe tardive symptoms). I have never seen Seroquel cause any kind of EPS symptoms (let alone TD), but then again, I seldom see Seroquel used as a sole agent.
>
> The worse case of TD that I had ever seen (the person could not even keep a hat of their head) was basically "cured" using Clozaril™ (clozapine). It did take over 8 months for the effects to kick in, but now this person is riding a bike, and if you did know that this person had TD, you couldn't tell. The transformation was absolutely amazing.
>
> I have heard a similar story with Zyprexa™ (olanzapine), but I have personally only seen the unmasking of Orap™ (pimozide) induced TD with Zyprexa. This could be due to the short time that the person was taking the Zyprexa before stopping it.
>
> - Cam


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