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Re: buprenorphine stuff » Elizabeth

Posted by Cisco on April 5, 2002, at 16:19:30

In reply to buprenorphine stuff, posted by Elizabeth on April 4, 2002, at 19:58:55

Elizabeth:

> The answer to what?

When I asked, not long ago, what was the effect of Buprenorphine's potent 'Kappa Antagonism', you responed with "Absence of effect at the Kappa Receptor".

> Dare I ask who wrote this?
Dare you may: I'll go back and find the Author. Probably some Wack-O Hack-O-Matic.

> Of course it is; buprenorphine blocks the effects of endogenous kappa agonists. I think that Goodman & Gilman has a table listing some of the effects of the different opioid receptor subtypes, but I'm not sure where my copy went.

If you were aware of this, why then the terse reply to my earlier question??

Buprenorphine and Effexor combined: Could it be the cutting edge treatment for TRD?

Cisco


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