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Re: buprenorphine stuff » Elizabeth

Posted by shelliR on April 5, 2002, at 20:56:48

In reply to buprenorphine stuff, posted by Elizabeth on April 4, 2002, at 19:58:55

> Is this medicine habit forming?

>That probably depends what you mean by "habit forming." But most likely, no it isn't. (A partial agonist is a drug that activates a receptor but doesn't cause the maximum effect at that
receptor.)<

I guess I would define habit forming in two ways.

Can you get off it once you start it: according to the information of Alexander Bodkin et.al, there is little withdrawal compared to full opiates.

Do people have to increase dose?

In the case studies of the 4 or 5 successful outcomes with buprenorphine (out of 7 who stayed in the study), most users did have to increase. At least one or two significantly over months and in one case through out a five year period.

Shelli


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