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Nortrip vs. other TCAs on H1 and Ach Blockade » johnj

Posted by fachad on June 12, 2002, at 23:00:15

In reply to Re: Norty compared to trimp (fachad), posted by johnj on June 12, 2002, at 9:04:58

Here is the earlier table with nortrip and benedryl added for comparison:

Drug------H1------Ach

Ami---------91------5.1
Dox--------410------1.3
Trim-------370------1.7
Nortrip-----10------0.7
Benadryl-----7---------
Atropine-------------42

I have no idea what the underlying mechanism of the exercize problem could be. The only thing you could do is to try other meds.


> Fachad:
>
> That is great info you posted. I was hoping you could post the same type of info (ACh, H1) for nortry as compared to the others?
>
> I might have told you, but here is my problem: I get severe rebound of side effects and mood disturbance when I excercise. It takes days to recover and usually it doesn't hit until a day or so after working out. I get dizzy, sleep disturbance and then mood decline.
>
> I have heard from two other people one on amit.(nortry mother drug) and one on notryp that had the same or similar problem. One person told me they didn't get this effect on imipramine, but I had some terrible jitterness and night sweats when I added just a few 10 mgs of impramine to my norty. Is that an Ach effect?
>
> Maybe it is the NE reuptake? As you said amit metabolizes to despramine so the combo has high NE reuptake. I am seriously looking at adding some trimp since I have had trouble sleeping, but I added some omega 3's last week and had to up my benzo a bit and have slept better. I thought the omega 3's were just crap, but I may have to re-evaluate that. Anyway, I would like to switch(with my docs help) and see if things stabilize and then try working out again. It is a mystery why excercise hoses things up, and the doc doesn't quite believe me. This has been going on for years so I know it is not in my head. I may find it is just TCA's that do it or I may find it is just nortry for some odd reason. Well, thanks for reading my rambling. Take care and keep us posted on your trimp dosing. Thank you
> Johnj


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URL: http://www.dr-bob.org/babble/20020609/msgs/109649.html