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Re: Prozac, Codeine, cyp2d6..CamW or anyone ?

Posted by katekite on August 1, 2002, at 19:10:10

In reply to Re: Prozac, Codeine, cyp2d6..CamW or anyone ? » janejj, posted by Cam W. on July 31, 2002, at 20:12:51

I'm on a big kick about effects of hormones lately and obsessive interest easily leads to far fetched ideas (well at least for me), so take this idea with a grain of salt, LOL.

Just was thinking that ssris will often normalize the HPA (adrenal) axis when they work. Since cortisol is an anti-inflammatory adrenal hormone that can be elevated or out of whack in general in depression, alcoholism and anxiety, normalizing (probably decreasing production) it might make you naturally start to feel pain more. More cortisol (like a cortisone shot) equals less pain, so maybe less cortisol would mean more pain.

An odd hypothesis of mine since headaches are painful and ssris are used in migraine prevention.

Many grains of salt.

kate


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URL: http://www.dr-bob.org/babble/20020731/msgs/114858.html