Posted by Ron Hill on February 25, 2003, at 12:11:41
In reply to NADH-3 Q's for responders... NonResponder Q too, posted by michael on February 24, 2003, at 22:57:58
Michael,
> To those who have had success w/it:
That's me!
> How much / often do you take it? (i.e.: 5mg twice a day?)
I started out taking 10 mg/day of the sublingual formulation (EnadAlert NADH). After ten days, however, this dose (and formulation) induced irritability. So I switched to one 5 mg enteric-coated Enada NADH tablet per day. After four weeks of remarkable results in the treatment of my atypical depression (low motivation, anergy, anhedonia, hypersomnia) and dysphoric mood states (extreme irritability), I began to get VERY sleepy about four hours after my dose. Therefore, I skipped my dose for two days. The sleepiness went away the first skipped day and the positive benefits remained. I'm currently in the process of determining the best dose for me.
Ray Sahelian, M.D., in his book titled "Mind Boosters: A Guide to Natural Supplements that Enhance Your Mind, Memory, and Mood", recommends taking no more than 2.5 mg two or three times per week. His main concerns regarding higher doses are the potential for building a tolerance to NADH and that the medical community doesn't know a lot about this stuff yet. My preliminary assessment is that I'll probably end up taking about 2.5 mg three times per week as a maintenance dose. Time will tell with regard to the dose and whether this stuff has any long-term effectiveness.
> How much time before before you were able to notice its effects?
I felt my atypical depression begin to lift within thirty seconds after placing the sublingual tablet under my tongue. Within three days, my depression and dysphoric mood states were in complete remission. It snapped me out of a three-month long bout with a deep depression that I just could not pull myself out of.
> What other meds do you take w/it?
I'm BP II and I take 600 mg/day of Lithobid. I think the Enada NADH might have pushed me (as a BP II) into hypomania if I had not had a moodstabilizer fully in place beforehand.
> Thanks for any feedback.
Michael, was it Enada NADH that you tried previously, or was it some other type of NADH? The reason I ask is that Enada NADH is the only stabilized and orally absorbable form of NADH currently available. It is, however, licensed to many different distributors so several brand names of Enada NADH are on the market. Prior to the development of the stabilized enteric-coated Enada NADH tablets, NADH could only be given intravenously because stomach acid would rapidly destroy the delicate molecule.
Best wishes.
-- Ron
poster:Ron Hill
thread:202372
URL: http://www.dr-bob.org/babble/20030224/msgs/203711.html