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adapton or DLPA experiences or knowledge?

Posted by avid abulia on June 15, 2003, at 16:33:56

adapton is a french drug, an extract of a fish of the genus *garum*, which contains peptides converted into endorphins once in the brain. it is cheap to import, and has been shown to be effective in acute stress and in inattention, but little research has been done regarding effects on depression or other disorders.

DLPA is a mixture of the d- and l- isoforms of the amino acid phenylalanine. l-phenylalanine can be converted into the trace amine phenylethylamine, which is both a naturally occurring amine protected by MAO-B inhibitions, as well as a metabolite of the mixed-MAO inhibitor Nardil. it can also be converted to the non-essential amino acid tyrosine, which is necessary to produce dopamine, adrenaline, and noradrenaline, as well as thyroxine. the d-phenylalanine is an inhibitor of enkephalin breakdown, and DLPA has had clinical studies showing it`s efficacy as an antidepressant and also for inattention and chronic pain, BUT as it contains a d-isoform of an amino acid, i am wondering if anyone knows if it has long-term toxicity? i have been unable to find any indications one way or the other.

as i am unable to take either conventional antidepressants or conventional stimulants because of a seizure disorder, and i have a chronic though episodic pain disorder with no real treatment available, i am wondering if anyone here has tried these, what their experiences were, and if they think potential benefits outweigh potential risks in my situation.

~AA


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poster:avid abulia thread:234152
URL: http://www.dr-bob.org/babble/20030614/msgs/234152.html