Posted by linkadge on January 8, 2004, at 9:03:21
In reply to Re: Thoughts on the 5h2a receptor, posted by SLS on January 8, 2004, at 8:15:20
Not exactly sure why that is then.
From my understanding (a few studies I will look for), SSRI's were effective for OCD but that effect was diminished/reduced when a 5ht2a receptor blocker was added, Ie trazodone, periactin etc. Perhaps, of the tryciclics, anafranil exerted the most 5ht2a agonism - regardless of its blocking capabilities.
I could be wrong :), but my understanding was that many drugs such as mirtazapine, and trazodone were innefective for OCD (expecially where sexual cotnent was involved in symptoms).
I suppose this effect would need to be studied specifically.
Linkadge
poster:linkadge
thread:297739
URL: http://www.dr-bob.org/babble/20040105/msgs/298019.html