Posted by Iansf on January 8, 2004, at 19:41:35
In reply to Re: Thoughts on the 5h2a receptor » linkadge, posted by Sad Panda on January 8, 2004, at 7:41:03
> According to
> http://www.psychotropical.com/notes/628.html
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> 5-HT2A receptors
>
> Studies using sleep EEGs on new drugs like nefazodone and mirtazapine suggest that 5-HT2A blockade produces an improvement in sleep patterns that is clinically useful. Many antidepressant drugs have such properties, data as below. Low numbers means high potency, ie bigger effect.
> Many neuroleptic drugs, both old and new, are also potent 5-HT2A blockers.
>
> Trazodone 25
>
>Does anyone know if the typical trazodone dose used for sleep (25mg-100mg)would effectively block 5-HT2A? Or would you have to take a therapeutic dose to get the blocking effect?
Someone also mentioned periactin for blocking 5-HT2A. How much of that is needed?
Thanks.
Ian
poster:Iansf
thread:297739
URL: http://www.dr-bob.org/babble/20040105/msgs/298329.html