Posted by MARKED on January 19, 2004, at 2:13:00
In reply to Re: MOCLOBEMIDE with TRILEPTAL ?? Dr. BOB HELP, posted by Maxime on January 18, 2004, at 23:02:05
Very good to get some feedback, I appreciate it all.
I read both your posts :)Ok, a couple of people have mentioned parnate with trileptal......(maoi & anti-epileptic).
I am not sure if everyone is aware, but Moclobemide is a RIMA (reversable mono-amide oxidase inhibitor, specifically reversable A blocker (but partially reversable B blocker), and not at all a MAOI (wich are not reversable).
It's promising that you are finding the combination helpful....and i also agree, most psychdocs stay away from these combinations as they can easily highten mania or heart rates. But my question is more to do with the RIMA's and their safety (which genarally i'd think is much safer than MAOI's). But thanks, and keep us informed of your progress.
Also, because Trileptal has effects on the liver, this causes other drug interraction to be speed up, and metabolised. Also i'd say a controlled diet would be needed, because of the salt reduction effects, and possible increased heartbeat.
Mark
> I responded to your other post but wanted to add here that there is no problem taking the two. I am bipolar and taking Parnate with trileptal.
poster:MARKED
thread:302044
URL: http://www.dr-bob.org/babble/20040118/msgs/302584.html