Posted by Karen Moore on January 24, 2004, at 20:09:37
In reply to Re: Pseudoephedrine and ADD, posted by scott-d-o on January 23, 2004, at 20:59:23
Scott,
Do you have any knowledge or any good resources on how Seroquel specifically effects dopamine levels/recepters depending on dosage? Is it possible that it is actually dopaminergic at low doses?! That would explain a few things... I'm also wondering if there might be a strange counterproductive interaction btween seroquel and amphetamine (adderall)...
Thanks,
km
>
> Well, most antipsychotics lower dopamine transmission but they can also increase it depending on the dosage you take. However, most of the antipsychotics also effect serotonin, noradrenergic, and even acetylcholine receptors. They also effect dopamine in a much different way than stimulants and I've never heard of any of them being efficacious for ADD. Your right about Wellbutrin being a dopamine reuptake inhibitor, however, it is an extremely mild one at that. It has a much greater impact on noradrenaline (like pseudoephedrine), which I'm sure is the source of any cardiac problems you may have had with the drug. I found Wellbutrin made me manic, while Adderall (a mixture of dextro and levo amphetamine salts) had a calming, focusing affect and almost made me want to go to sleep-- at lower doses of course.
>
> scott
poster:Karen Moore
thread:302237
URL: http://www.dr-bob.org/babble/20040122/msgs/305153.html