Posted by jerrympls on March 23, 2004, at 19:45:21
In reply to Re: Dopamine Agonists Mirapex » bertill33, posted by Ame Sans Vie on March 23, 2004, at 9:42:26
>
> You mentioned Mirapex -- my experience with it was wonderful at first. It definitely provided me with a ton of motivation and a great sense of purpose. But after a couple months or so, I began having the dreaded sleep attacks that King Vultan alluded to in his post. Maybe adding on Provigil or another CNS stimulant would have helped, but I guess I'll never know now -- my medication regimen at the moment is perfect. I took 1.5mg three times daily. You have to titrate your dose upward *very* slowly, unless you want to be lying on your bathroom floor with the most horrible, unrelenting nausea ever for six hours like I did several times when just beginning treatment. From what I understand Requip, which acts very similarly to Mirapex (i.e. it agonizes the same dopamine receptors), is not a whole lot different. And from what I hear, the same usually goes for Dostinex (cabergoline) and Parlodel (bromocriptine), but they aren't typically very useful for increasing motivation as they aren't as selective about which dopamine receptors they target.
>>
> One important drug to consider is Symmetrel (amantadine). It is an antiviral and Parkinson's drug that actually causes *release* of dopamine. This has potential to be extremely helpful.
>Michael-
I've been wanting to get in touch with you regarding your experiences with Mirapex. I seemy pdoc this Friday and Mirapex or Amantadine may be a choice. I'm currently on 375mg of Effexor, 40mg Valium, 300 Seroquel (for sleep!) and 56mg of Concerta. I've heard so many positive things about Mirapex for depression - especially for those with severe apathy, lethargy, etc. But then I read in your posts that after a couple months or so you started to fall asleep in the middle of the day - why? What is it about Mirapex - or dopamine agonists - that would cause this? How ould you compare Amantadine to Mirapex? I've heard the side effects of Mirapex are not the greatest.
I'd be SOOOOO pleased if you responded here or emailed me (jerrympls@mn.rr.com).
Thanks so much!!!
Jerry
poster:jerrympls
thread:327293
URL: http://www.dr-bob.org/babble/20040319/msgs/327535.html