Posted by Michael Bell on May 29, 2004, at 16:33:12
In reply to Re: GHB(xyrem) vs. ALCOHOL » btnd, posted by zeugma on May 29, 2004, at 16:00:55
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I know you asked about Provigil. I haven't taken that, but I do have a lot of experience with Adrafinil. Taken in combo with Amisulpride & Klono, it works pretty well for SP. However, its prosocial effects were inconsistent and fleeting. Sort of like a toned down version of the Adderall I'm taking now. And that's really the problem, right? Other than Nardil,(and Xyrem, according to btnd and others), there really isn't a single drug that attacks both the anxiety and reward deficiency part of social phobia with great efficacy.Right now, I take Klono & Adderall. Many people have said this combo is very prosocial for them. However, I find that the Adderall is making me hyperfocus and somewhat *less* social. I'm wondering maybe I've become tolerant to the prosocial effects and if adding memantine to the combo will alleviate that. I'm expecting a shipment of memantine to arrive shortly, so I'll keep the board posted.
Thanks for the info about xyrem, I have looked at the PI sheets and followed some of the links which are very useful.
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> It seems that Xyrem and benzodiazepines are contraindicted. Also, TCA's (because they are sedatives). Xyrem, like clonazepam, caused depression in some who participated in clinical trials, unsure what to make of this. Clonazepam may have aggravated my condition in some ways but improved it in others, I agree with you that it is not pro-social at all. In fact I want to isolate even more on it. But as I told my pdoc yesterday, it makes me feel more 'normal' around others, and nothing has ever had anything like this effect.
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> Have you ever tried Provigil? Does Provigil cause a pro-social effect, and if so, how does it compare to amphetamine?
poster:Michael Bell
thread:351654
URL: http://www.dr-bob.org/babble/20040527/msgs/351914.html