Posted by King Vultan on June 25, 2004, at 16:46:21
In reply to Re: Effexor withdrawal - Extreme Agression, posted by Doloris on Tuesdays on June 25, 2004, at 14:45:11
>
> > I've also been on 300 mg Wellbutrin per day and thought you might find it interesting that I eventually had to drop this med because of extreme irritability. In my case, this developed over a period of months, but I've read anecdotes from other people suggesting it can happen more quickly for some.
>
> Oh,my God,
> I wonder if this is happening to me? What would happen if I went off the 300mg of wellbutrin, too. Would I end up in a psycho ward?
> What are the side-effects of going off wellbutrin?
When I realized what was going on, I went down to 150 mg/day of the Wellbutrin (I was taking the SR version--2 x 150 mg/day), and the irritability immediately disappeared. Unfortunately, there was also a loss of antidepressant effect, such that within a couple of weeks, I was finding it very difficult to function. It was so bad I had to supplement with 25 mg Zoloft from an old supply in my bathroom cupboard until I could get in to see my pdoc. At that point, we decided to take a different approach and go on to the tricyclics.
I've taken doses of less than 300 mg/day of Wellbutrin since then to try to supplement other drugs and experienced zero withdrawal effects when dropping it. Wellbutrin works only on norepinephrine and dopamine, and it is mainly the antidepressants that work on serotonin that seem to have significant withdrawal problems, such as the SSRIs and Effexor.Todd
poster:King Vultan
thread:360067
URL: http://www.dr-bob.org/babble/20040621/msgs/360413.html