Posted by iris2 on August 25, 2004, at 18:00:03
In reply to Re: To Scott » iris2, posted by owensmar on August 25, 2004, at 15:40:03
Marsha,A lot of that stuff is over my head too. Especially the last couple of years as my cognitive skills declined with my continuing depression.
Not sure right now (memory!) if another word is used when a medication does not work again. I had a combination of not working as well and then having "holidays" and it finally not working at all. I also had an experience specifically with amineptine where it worked wonders the first time and I had to go off of it because of another disease. When I tried again (as you did) a few months later nothing, and tried again after a year or so and still nothing.
With certain drugs like the MAO's there is a chemical reason why this happens. Again both over my head and do not remember. I have not seen this about TCA's. I had a similar effect with Effexor as you. This is one of the reasons I considered taking either Milnacipran or Duloxetine. I think you should give those two some thought based on your experience with Effexor. I think your thinking is right on. By the way are you working with a pdoc.? Is he/she giving you good advice?
I do find that even among those that have a great understanding of the chemical changes meds make that there is generally not a great amount of being able to link that knowledge to prescribing decisions. I know a little bit and I hope you are aware of this, not a lot. This is just not an exact science.
I hope you’re in a better place soon. I am not functioning at all. Except I do not want to die all of the time anymore either.
irene
p.s.If I post back to you again I will laeve poor Scott's name out of the subject heading!!
poster:iris2
thread:378449
URL: http://www.dr-bob.org/babble/20040825/msgs/382303.html