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Re: glutamate inhibitors, glutamate releasers

Posted by TheOutsider on September 11, 2004, at 16:55:23

In reply to glutamate inhibitors, glutamate releasers, posted by linkadge on September 11, 2004, at 15:38:44

> How is it that two, totally opposite mechanisms of a drug can provide antidepressant properties. Drugs like modafanil cause a release of glutamate and have antidepressant properties. On the other hand, drugs like riluzole reduce glutamate activity and have antidepressant properties.
>
> I'm confused
>
> Linkadge

I don't have any scientific evidence to back this up, its just a theory!
Perhapse different kinds of depression could be related to both a shortage, and an overabundance of glutimate.
Maybe anxious depressives have to much glutamate, and lethargic depressives have to little? Just an idea


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poster:TheOutsider thread:389725
URL: http://www.dr-bob.org/babble/20040909/msgs/389753.html