Posted by ed_uk on December 5, 2004, at 14:59:11
In reply to Re: Parnate, Nardil and dietary restrictions?!, posted by jclint on December 5, 2004, at 10:59:30
Hi Ted and Jclint :-)
Jclint summarises the important points...
'- There is little clinical research into Parnate's effeciacy in SA, but quite a lot into Nardil's
- Parnate is apparently less forgiving in terms of dietary restrictions
- Parnate generally causes more insomnia than Nardil'......... I have often wondered how important the GABAergic effect of Nardil is in social anxiety. The GABAergic effect of Nardil is *not* the same as a benzodiazepine. Unlike Parnate, Nardil is a GABA transaminase inhibitor which means that it inhibits the breakdown of GABA. In the UK, an anticonvulsant called vigabatrin is available- it is a GABA transaminase inhibitor. Behavioural/psychiatric side effects are very common. Ahhh :-(
Some of the common side effects of vigabatrin are...
drowsiness, fatigue, dizziness, anxiety! aggression, depression and headache. Less common side effects include... psychosis, amnesia, double vision, weight gain! and agitation.
Of course, vigabatrin and Nardil are different drugs but to be honest.... I'm not sure that I want to take a GABA transaminase inhibitor.
Regards,
Ed.
poster:ed_uk
thread:424658
URL: http://www.dr-bob.org/babble/20041201/msgs/424819.html