Posted by linkadge on December 6, 2004, at 14:00:33
In reply to MAOIs and aggression, posted by ed_uk on December 6, 2004, at 13:48:36
I was just about to post the exact same thing. When you mentioned the SSRI's/agression link in some of the above posts I thought It might be advantageious to mention that there has been a link found in both animals and humans, between low MAO-A and agression, particulary agression under stress.
An MAO-A inhibitor would have a similar effect to say effexor, raising norepinephrine and serototonin. Yes I did find that effexor made me more agressive, not physically, but verbally, and just the way I felt about myself. I felt *meaner*
and more "punklike"Serotonin at the 5ht1a,1b receptors can *tame* agresssion, but serotonin particularly at the 5-ht2c receptor can cause agression.
It is interesting (and almost paradoxical in our thinking) to find that MAO-B inhibitors have *not* been linked to agression.
I would think that a perfect serenic would be a 5-ht1a/b receptor agonist combined with a selective MAO-B inhibitor.
Linkadge
poster:linkadge
thread:425286
URL: http://www.dr-bob.org/babble/20041206/msgs/425293.html