Posted by SDW on December 8, 2004, at 17:31:30
To anyone who has had an AD poop-out over the course of long-term treatment, or had residual dysthymia/anhedonia while on meds, I am wondering what others might consider doing in my shoes:For the last 2 years I have had a moderate chronic depression (dysthymia) characterized by:
Severe Fatigue
Apathy-Anhedonia
Zero Motivation
Memory /Concentration ProblemsI have been taking Amphetamine in order to function with the fatigue, but it does nothing for the depression.
I have used Parnate for severe major depression in the past and have had a great response, but it hasn’t helped me with this current illness. I have tried augmentation with Lithium, Lamictal, Cytomel. Cytomel was the only thing that offered any additional benefit, but it was modest. I tried a few SSRI’s and TCA’s in the past without much success.
I just restarted Parnate 3-4 weeks ago after a 5-month break hoping it might work at a higher dose. My doc will go up to 100 mg or so; I just went from 80 to 90. If it does not work after a few weeks at 100mg, I am considering:
MIRAPEX or Other DA Agonist
WELLBUTRIN
SNRI (CYMBALTA)
NARDIL(POSSIBLY)
My official diagnoses: Major Depression, Recurrent; Dysthymic Disorder.After 2 non-stop years, I am really desperate and I don’t want to sink into MD Episode. I am trying (slowly) to come to terms with the fact that Parnate may not help anymore, and maintain hope that something else will.
I appreciate any similar experiences /ideas / etc…
Steve
poster:SDW
thread:426320
URL: http://www.dr-bob.org/babble/20041206/msgs/426320.html