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Re: diminishing tolerence to opiates

Posted by reefer on December 17, 2004, at 17:07:38

In reply to Re: diminishing tolerence to opiates, posted by SLS on December 17, 2004, at 16:25:47

Yes memantine works for preventing opiate tolerance. This is by blocking NMDA receptors. Another thing that works good for this is DXM (dextromethorphan) which also blocks NMDA receptors. I've only read about DXM + morphine so i'm not sure if it will work to block tolerance with other opioids. DXM is noramally a cough medication. Search google for +dxm +morphine and you will get loads of info on this.


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URL: http://www.dr-bob.org/babble/20041217/msgs/430964.html