Posted by King Vultan on January 16, 2005, at 22:56:11
In reply to Zyprexa and Metabolic Syndome, posted by sdjeff on January 16, 2005, at 22:44:20
> Hi,
>
> I've been taking Zyprexa for about 6 months. In that time, I've gained almost 30 pounds and according to my last blood tests, I've developed Metabolic Syndrome.
>
> I don't know what to do. I don't know if this is grounds for stopping this med. If I had to, I don't know what else I could try. Abilify, Geodon and clozaril are out. I can't afford to gain any more weight. Any ideas?
>
I believe you would find Risperdal to have a much lower tendency to cause weight gain, as it only has a weak histamine H1 blockade compared to the extremely powerful one of Zyprexa, and Risperdal does not blockade serotonin-2c receptors much at all (this particular blockade can sometimes increase appetite). Risperdal does have a tendency to increase prolactin levels, and it also has a higher indicidence of EPSEs than does Zyprexa, but I think it is still a relatively good drug and far superior to the old style/traditional antipsychotics in terms of overall side effects.Todd
poster:King Vultan
thread:442985
URL: http://www.dr-bob.org/babble/20050113/msgs/442989.html