Posted by Ron Hill on January 18, 2005, at 13:30:01
In reply to Re: Lamictal doesn't work anymore » catmint, posted by Ritch on January 15, 2005, at 15:46:25
Mitch,
> > By the way, have you heard from Colin lately?
> Yes, last time I posted to him he was looking for advice on adding a psychostim for bipolar depression, I think that was just about a week or two ago. Haven't heard back on it yet.
Mitch, did you really hear from Colin recently, or do you have me confused with my good buddy Colin? The most recent post I've seen from Colin was back in October:
http://www.dr-bob.org/babble/20041007/msgs/401578.html
Do you know of a more recent post?
It's no big deal if you've got us mixed up; we can write off the name recall glitch to the Depakote.
I feel bad that I didn't get back to thank you for your response to my former post regarding Adderall. I've had a very "interesting" response to the addition of 5 mg of Adderall. At some point I'll tell you all about it. My one-year protest is over sometime in February.
Thank you Mitch!
Hey in reference to your posts in a thread above, have you ever tried ginger on a prn basis to treat Trileptal induced nausa? I buy crystallized ginger at the grocery store in the bulk food section. It's a little spendie (about $7 per lb) but it does the trick on my rare bouts of nausa. YMMV.
I love two things about Trileptal; it reels in my hypomania within minutes of taking a dose and I sleep like a baby on it. As you are well aware, good sound sleep is an excellent bipolar "medication".
Unfortunately, Trileptal does not help my BPII atypical depression. In fact, it almost feels like it hinders me from cycling out of the depressive phase of my cycle. In other words, it kinda holds me in the depressive phase longer than I would have been without it. I notice this particularly at higher dosages. As a side note, I'm absolutely convinced that Depokote caused depression when I was on it years ago.
-- Ron
Bipolar II and Obsessive Compulsive Personality Traits
600 mg/day Lithobid
900 mg/day Trileptal
50 mg/day Lamictal
5 mg/day Adderall PRN for very short intervals (i.e.; about five days or so) as needed to chase away the bipolar atypical depression demons. The Adderall is discontinued as soon as the depression abates in order to avoid pstim induced burnout. (Note: the Adderall experiment is early in the trial, so time will tell.)
-------------------------------------------------
> > Hi Ritch,
> >
> > By the way, have you heard from Colin lately?
>
> Yes, last time I posted to him he was looking for advice on adding a psychostim for bipolar depression, I think that was just about a week or two ago. Haven't heard back on it yet. Oh, while the server was being switched I done some researching and there is derivative of Trileptal that is in clinical trials for bipolar.. it is licarbazapine. You may have read a few days ago about the approval of a unique extended-release form of carbamazepine for bipolar (can't remember the brand name now). Anyhow, here's some links related to licarbazapine.. I think they are still looking for volunteers for the trials..:
> http://www.clinicaltrials.gov/ct/gui/show/NCT00099229
> http://www.jclinpharm.org/cgi/content/abstract/44/8/906
> http://www.ingentaconnect.com/content/sage/j377/2004/00000044/00000008/art00010
>
> Here's a text clip related to licarb. :
> Novartis appear to have revived
> licarbazepine, the monohydroxy
> analog of oxcarbazepine, develop-
> ment of which was suspended in
> 1999 as part of a pipeline reorgani-
> zation process. Applications this year
> have expanded the indications from
> epilepsy to include tinnitus
> (WO2004014391)
> and
> pain
> (WO2004035041) and two applica-
> tions this week claim anxiety, bipolar
> disorder and neuropathic pain.
>
> Hmmm... it's interesting that they are pursuing an anxiety indication.... from what I read the side effect profile was supposed to be better than carbamazepine and oxcarbazepine. I'll be watching this one with interest for sure.
>
> Oh yeah! Felbamate is also in clinical trials now for Bipolar. Hope you get to feeling better! Do you think that the Lamictal is *causing* your agitation and irritability?
>
poster:Ron Hill
thread:441138
URL: http://www.dr-bob.org/babble/20050113/msgs/443733.html