Posted by KaraS on January 27, 2005, at 11:51:38
In reply to Segeline Patch, posted by verne on January 27, 2005, at 9:37:11
> I've googled this and get nowhere. Does anybody know if this is close to approval? And can it be prescribed for depression?
>
> Cymbalta isn't really working out for me. In addition to the sexual side effects, I've experienced sharp pains in the chest (heart?), and low back pain. (when I stopped cymbalta for a few days the back pain disappeared)
>
> Previous doctors wanted me to try an MAO Inhibitor but I resisted due to the diet restrictions and risk. My blood pressure runs on the high side so I don't want to risk a hypertensive crisis. I had heard that the newer MAO's don't have the diet restrictions and was hoping that segeline was among them.
>
> verneHi Verne,
Oral selegiline should not cause hypertensive crises on dosages of 10 mg. a day and under (though people should probably be careful in case they are slow metabolizers). Some people have had great success using that dosage along with some l-phenylalanine or DLPA. (If you do a search here you'll find some very informative and inspiring posts on this esp. by Ktemene, Pseudonym and Adam.)The other selective MAOIs that you are referring to aren't available in this country yet. Others on this board have tried them without much success though. If you search here for Moclobemide I doubt that you'll find many good posts.
As for the patch, Adam was using that as part of a drug trial and it changed his life. He had incredible results. Today (unless something has changed from his last post) he takes selegiline orally and is waiting for the patch to come out so he can switch over.
Take care,
Kara
poster:KaraS
thread:448571
URL: http://www.dr-bob.org/babble/20050124/msgs/448622.html