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Re: Zoloft - temporary problems or not?!?!? » blueberry

Posted by TamaraJ on July 11, 2005, at 19:26:06

In reply to Re: Zoloft - temporary problems or not?!?!?, posted by blueberry on July 11, 2005, at 19:00:04

Thanks, Blueberry. Unfortunately, I can't cut the pill in half, they are caps. But, they are 25mg caps, so I could go back to 25mg for a few days. I also just thought that maybe I could reduce the Wellbutrin to 100mg for a few days, while I adjust to the 50mg of the Zoloft. Would that also make sense? The other thing that may be exacerbating the side effects is that I have not yet completely quit smoking, so perhaps there is even more dopamine activity going on because of the smoking.

And, as you say, part of the problem could still be nortriptyline withdrawal. I stopped just over a week ago, going immediately from 75mg to 0. I have a question for you, if you feel you can answer. As I am adjusting to the Zoloft, I am finding that my sleep is not very restorative, and I wake up achy, exhausted and foggy. I wonder if I could take 25mg of the nortriptyline for a few days, or would that be unwise with the Zoloft?

Thanks so much.

Tamara

> If it were me, I would cut a pill in half and just do a half the next time. Stay there a few days at least before moving up. That's what I would do anyway.
>
> Wellbutrin is thought to be a dopamine reuptake inhibitor, and even though zoloft is a serotonin reuptake inhibitor, it actually does have some dopamine reuptake inhibition also. So maybe with the two combined you might experience something like a dopamine overload with rage and agitation and stuff. I would cut the dose back and approach it more gradually.
>
> There could be withdrawals from nortriptyline mixed in there confusing things. I was on nortriptyline for just a couple weeks, but went through some fairly tough withdrawals.


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