Posted by TamaraJ on July 12, 2005, at 20:36:21
In reply to Re: Question for Scott (if you have time) » TamaraJ, posted by SLS on July 12, 2005, at 18:37:28
Thanks, Scott. Your musings were interesting and useful. It is incredible just how much conflicting information there is on this particular AD. I seem to recall reading in two places that it is a weak inhibitor of dopamine and norepinephrine. Yet, I have heard the opposite as well. It may well have to do with the metabolites, and even that is a mystery I think because I seem to recall reading that there is also a second metabolite but nobody is sure what exactly it does. I imagine that Wellbutrin must be quite hard on the liver with all the metabolism it goes through.
Until I get through the start-up side effects from the Zoloft, it is difficult to say if the Wellbutrin is making me fatigued. I know in the morning after I take my Wellbutrin/Zoloft, I get really tired for a couple of hours. So, I will keep an eye on that. It may turn out that Zoloft (for the anticipatory anxiety and nameless dread) and Nortriptyline (for the depression and adhedonia) may be the right combo, but I will stick with the Zoloft/Wellbutrin until I have made it through the worst of the start-up side effects.
Thanks again. Your insights are much appreciated.
Tamara
poster:TamaraJ
thread:525731
URL: http://www.dr-bob.org/babble/20050708/msgs/526906.html