Posted by Chairman_MAO on September 16, 2005, at 10:25:53
In reply to Re: opiates, my cure for depression, posted by Declan on September 13, 2005, at 23:46:36
I always liked oxycodone better, although I could see how hydrocodone's stimulant nature could prove better for some people. Frankly, I've tried a lot of opioids (not fentanyl though) and nothing beat heroin. I have heard oxymorphone is generally the best.
Buprenorphine is honestly the best given our current sociopolitical situation re: opioids. Also, it is a kappa antagonist, which confers antipsychotic (and I think additional antidepressant/antimanic properties). It is also advantageous as it does not induce hypogonadism with long-term administration as most full agonists do. See:
http://jcem.endojournals.org/cgi/content/abstract/90/1/203
poster:Chairman_MAO
thread:460626
URL: http://www.dr-bob.org/babble/20050914/msgs/555633.html