Posted by pseudoname on November 22, 2005, at 7:12:56
In reply to Re: dopamine, coffee, and wellbutrin? » spriggy, posted by lunesta on November 22, 2005, at 3:26:17
lunesta, do you mean coffee/caffeine when you say this?
> doesnt work via dopamine @ all
Can you say what you mean or what you're referencing? Thanks.
Caffeine unquestionably involves dopamine; its antidepressant effect is most likely tied to DA release in the prefrontal cortex. And the fact that caffeine blocks adenosine doesn't mean that caffeine doesn't also "work via" DA. (Caffeine doesn't necessarily "reduce" adenosine, as you say; it just acts as a nonselective adenosine receptor antagonist.)
poster:pseudoname
thread:580785
URL: http://www.dr-bob.org/babble/20051119/msgs/581169.html