Posted by lunesta on November 24, 2005, at 13:26:41
In reply to caffeine reading » lunesta, posted by pseudoname on November 23, 2005, at 18:23:48
I am sorry if I came across as if it was a fact. The evidence you cite doesnt personally convince me of dopamine involvement in the rewarding and antidepressant effect of caffeeine. Dopamine is involved in every addiction, so you cant always go back on it as a failsafe. What receptors does it effect exactly, auto receptors, post synaptic? is it in an area that matters?
Anytime you slow done adenosine and increase brain energy and excitation you will have a rise in neurotransmitters, so that is a given IMO.
Again, sorry if i was a bit blunt but unless you can cite more evidence, i dont think caffeines antidepressant activity is via dopamine? Unless, are you saying, the other compenent in coffee, or chcolate, i think its called theobormide or something, now that is something. Again, if you can post the article #'s from medline/pubmed or a scientific journal and not a random web writeup i would love to look into this more and learn.
lunny
poster:lunesta
thread:580785
URL: http://www.dr-bob.org/babble/20051119/msgs/581879.html