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Re: this is interesting

Posted by linkadge on February 21, 2006, at 16:47:53

In reply to Re: this is interesting » linkadge, posted by zeugma on February 21, 2006, at 13:50:19

>did you find that your attention/focus was >improved while undergoing rTMS?

Yes, my concentration improved imedately, but my actually cognition and comprehention improved later. It was like I was using different parts of my brain to process information, and that those areas hadn't been worked in a while.

>then one would expect it to be especially good >for the most severe depressions.

It is kindof variable, even like ECT. There have been those who have failed ECT and responded to rTMS, and vice versa. There will, of course, be people who fail both.

>a while ago (maybe thirty years) there was a >beta adrenoceptor hypothesis of AD action. there >still is one, apparently, in panic disorder: the >only AD's (so called) that are not also >antipanic agents are trazodone, bupropion, and >buspirone (buspirone is considered an AD by many >investigators, and i agree) and none of these >down regulate beta adrenoceptor receptors. so >perhaps rTMS is an antipanic treatment as well?

Yes perhaps. It is really dumb because I think that the beta-adrenorceptor theory was replaced by the theory about 5-ht2 system downregulation only after the advent of the SSRI's.

Beta adrenoreceptor density may not be a result of circulating norepinephrine though, since I have read that NMDA antagonists can downregulate adrenoreceptors.


>(although I wonder if AP's are also antipanic >agents, and clonazepam is a most powerful
>antipanic agent)

I personally found no anti-panic effect of the antipsychotics. Some of them made my panic disorder worse. Exercise has anti-panic effects, and it too reduces adrenoreceptor density, among other things.


>yes, that is surprising. given that the >hypnagogic hallucinations/ sleep paralysis I >experience with distressing frequency on >Provigil feel like electrical shocks sometimes, >and leave headaches and insomnia in their wake, >I would be most reluctant to apply an electrical >device to my skull. that is just my own >prejudice.

I've regretted doing it, entering bouts of paranoia that I will end up with a brain tumor one day.


Linkadge


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poster:linkadge thread:611154
URL: http://www.dr-bob.org/babble/20060219/msgs/611806.html